نتایج جستجو برای: ht1 receptor

تعداد نتایج: 590501  

Journal: :Genetics 1988
K S McKim A M Howell A M Rose

In the nematode Caenorhabditis elegans, recombination suppression in translocation heterozygotes is severe and extensive. We have examined the meiotic properties of two translocations involving chromosome I, szT1(I;X) and hT1(I;V). No recombination was observed in either of these translocation heterozygotes along the left (let-362-unc-13) 17 map units of chromosome I. Using half-translocations ...

2014
Dong-yep Oh Yoon-seok Lee Boo-mi La Jea-young Lee Yong-soo Park Ji-hong Lee Jae-jung Ha Jun-koo Yi Byung-ki Kim Jung-sou Yeo

The thyroid hormone responsive protein (THRSP) gene is a functional gene that can be used to indicate the fatty acid compositions. This study investigates the relationships of exonic single nucleotide polymorphisms (SNPs) in the THRSP gene and fatty acid composition of muscle fat and marbling score in the 612 Korean cattle. The relationships between fatty acid composition and eight SNPs in the ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1999
P L Durham A F Russo

We have investigated the regulation of calcitonin gene-related peptide (CGRP) release from trigeminal neurons by the serotonergic antimigraine drug sumatriptan. Serum levels of the neuropeptide CGRP are elevated during migraine. Treatment with the drug sumatriptan returns CGRP levels to normal coincident with the alleviation of headache. However, despite this clinical efficacy, the cellular tar...

2014
Christian Scharinger Ulrich Rabl Christian H. Kasess Bernhard M. Meyer Tina Hofmaier Kersten Diers Lucie Bartova Gerald Pail Wolfgang Huf Zeljko Uzelac Beate Hartinger Klaudius Kalcher Thomas Perkmann Helmuth Haslacher Andreas Meyer-Lindenberg Siegfried Kasper Michael Freissmuth Christian Windischberger Matthäus Willeit Rupert Lanzenberger Harald Esterbauer Burkhard Brocke Ewald Moser Harald H. Sitte Lukas Pezawas

BACKGROUND The serotonin transporter (5-HTT) is abundantly expressed in humans by the serotonin transporter gene SLC6A4 and removes serotonin (5-HT) from extracellular space. A blood-brain relationship between platelet and synaptosomal 5-HT reuptake has been suggested, but it is unknown today, if platelet 5-HT uptake can predict neural activation of human brain networks that are known to be und...

2015
Chang Ho Min YiYi Wang Jinhyung Bae Jung Hoon Han Uy Dong Sohn

To see the inhibitory mechanism of gentamicin in response to electrical field stimulation (EFS) using the rat bladder smooth muscle, atropine or guanethidine was treated but had no effect. Methylsergide, a non-selective 5-HT1, 5-HT2 receptor antagonist was also treated but had on effect. Kinase inhibitors, such as chelerythrine (PKC inhibitor), ML-9 (MLCK inhibitor), or Y27632 (rho kinase inhib...

2009
Robert R. Gibboni Prisca E. Zimmerman Katalin M. Gothard

Scanpaths (the succession of fixations and saccades during spontaneous viewing) contain information about the image but also about the viewer. To determine the viewer-dependent factors in the scanpaths of monkeys, we trained three adult males (Macaca mulatta) to look for 3 s at images of conspecific facial expressions with either direct or averted gaze. The subjects showed significant differenc...

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