Hepatic stimulator substance (HSS) protects liver cells from various toxins. However, the mechanism by which HSS protects hepatocytes remains unclear. In this study, we report that the HSS gene, after transfection into BEL-7402 hepatocma cells, is stably expressed in the mitochondria. Hydrogen peroxide (H(2)O(2))-induced cell apoptosis in the HSS-transfected cells is reduced, as shown by morpho...

BACKGROUND The mechanism of cadmium-induced liver regeneration arrest in relation to hepatic stimulator substance (HSS) biological activity was investigated. MATERIALS AND METHODS In Wistar rats subjected to 65 - 70% partial hepatectomy, saline, cadmium, cadmium and HSS were administered. The rats were also subjected to 30 - 34% partial hepatectomy. Mitotic index, immunochemistry for PCNA, 3[...

Cell motility depends on the rapid growth of cortical actin filaments whose barbed ends are capped in the resting cell. High speed supernates (HSS) of dilute neutrophil lysates contain actin monomers and/or oligomers that can be induced to polymerize by certain stimuli. We questioned whether some of the actin remaining in the supernate after high speed centrifugation exists as occult nucleation...

One of the biggest problems of artisans , is notching the high speed steel roller is due to the inability to do this work, become high speed steel roller bearings are disposable. One of the biggest problems of artisans , is notching the high speed steel roller is due to the inability to do this work, become high speed steel roller bearings are disposable.When the roller is placed on the product...

In literature the influence of curvature on formability has been reported. This paper shows results for four materials when an FLC is measured with increasing curvature. It shows the FLC increases for sharper curvature most notably with 20 [mm] tool diameter. The increase is negligible on the left hand side, moderate on the right hand side and large on the plane strain axis. It is thought that ...

In this research work a series of tests were conducted in order to determine flank wear and cutting force FY on hard AISI 440 C martensitic stainless steel and SCM 440 alloy steels. The operating parameters are cutting speed, feed rate and a constant depth of cut to investigate the flank wear and cutting force. No cutting fluid was used during the turning process. The cutting tool used was CBN ...

Drilling is an hole making process in metal cutting operation performed by extrusion which finds wide application in various industries for manufacturing components using metals and non metals. This process is applied widely in assembly of components or elements, where processing challenges are severe issue such as to maintain surface integrity, ovality, machining time, Metal Removal Rate etc.,...

Surface Plasmon Polaritons (SPPs) have been known since the late 1950s with the work of Richie [1]. Today most research with these surface waves is aimed at production of subwavelength components in an attempt to merge the subjects of electronics and photonics on a nanometer scale. However, the features produced by SPPs could have uses in direct engineering applications due to their surface tex...

To increase the tool life of fine blanking punches, this work investigates a combined solution approach consisting increasing mechanical strength substrate material by shot peening and deposition physical vapor (PVD) hard coatings. A powder metallurgical high-speed steel (HSS) is used as material. First, temperature-dependent relaxation behavior residual stresses strain-hardening shot-peened an...

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