Programming tools for High Performance Computing are lagging behind the tools that have improved the productivity of desktop programmers. The increasing complexity of HPC codes, the growing number of cores that they must utilize, their long life-span, and the plethora of desirable source code optimizations and hardware platforms make HPC codes hard to maintain. Refactoring tools can enable HPC ...

Cloud computing has emerged as a new paradigm in large-scale computing. Highperformance computing (HPC) is an important research tool for a variety of fields. HPC requires a large investment in specialized computing infrastructure. While these costs could be alleviated by commercial cloud computing environments, standard clouds have extremely variable latency and reliability characteristics and...

H uman leukocyte antigen (HLA) matching is critically important for successful hematopoietic progenitor cell (HPC) transplantation because the rates of engraftment and transplant outcomes are strongly influenced by the degree of match. This is largely because HLA antigens are expressed on immature pluripotent stem cells. In contrast, ABO incompatibility is not a barrier to successful HPC transp...

This paper describes an automated approach to handling Big Data workloads on HPC systems. We describe a solution that dynamically creates a unified cluster based on YARN in an HPC Environment, without the need to configure and allocate a dedicated Hadoop cluster. The end user can choose to write the solution in any combination of supported frameworks, a solution that scales seamlessly from a fe...

In this paper, we describe a trilogy of Massive Open Online Courses (MOOCs) that together expose knowledge and skills of fundamental importance to HPC. Linear Algebra: Foundations to Frontiers (LAFF) covers topics found in an introductory undergraduate course on linear algebra. It links abstraction in mathematics to abstraction in programming, with many enrichments that connect to HPC. LAFFOn P...

Virtualization has gained increasing attention in the recent High Performance Computing (HPC) development. While HPC provides scalability and computing performance, HPC in the cloud benefits in addition from the agility and flexibility that virtualization brings. One of the major challenges of HPC in virtualized environments is RDMA virtualization. Existing implementations of RDMA virtualizatio...

The hippocampal formation (HPC) and medial prefrontal cortex (mPFC) have well-established roles in memory encoding and retrieval. However, the mechanisms underlying interactions between the HPC and mPFC in achieving these functions is not fully understood. Considerable research supports the idea that a direct pathway from the HPC and subiculum to the mPFC is critically involved in cognitive and...

Although unusual, hemangiopericytoma (HPC) can be considered benign or malignant depending on histologic features. In some cases, malignant HPC can behave as high-grade sarcomas. When HPC is deemed malignant, radical surgical excision is the treatment of choice. Adjuvant chemotherapy and radiation therapy offer limited success in patients with this malignancy. This article details a case study ...