Aim: Hemoglobin (Hb) becomes toxic when released from the erythrocyte. The acute phase protein haptoglobin (Hp) binds avidly to Hb and decreases oxidative damage to Hb itself and to the surrounding proteins and lipids. However, the molecular mechanism underpinning Hp protection is to date unclear. The aim of this study was to use electron paramagnetic resonance (EPR) spectroscopy, stopped flow ...

A highly parallelizable domain decomposition solution technique for adaptive hp finite element methods is developed. The technique uses good partitioning strategies and a subspace decomposition based preconditioned iterative solver, Two level orthogonalization is used to obtain a reduced system which is preconditioned by a coarse grid operator. Numerical results show fast cOIl\'ergence for the ...

We introduce a multiple interval Chebyshev-Gauss-Lobatto spectral collocation method for the initial value problems of the nonlinear ordinary differential equations (ODES). This method is easy to implement and possesses the high order accuracy. In addition, it is very stable and suitable for long time calculations. We also obtain the hp-version bound on the numerical error of the multiple inter...

The dispersion relation of the semi-discrete continuous and discontin-uous Galerkin formulations are analysed for the linear advection equation. In the context of an spectral/hp element discretisation on an equispaced mesh the problem can be reduced to a P P eigenvalue problem where P is the polynomial order. The analytical dispersion relationships for polynomial order up to P = 3 and the numer...

In this paper we formulate a high order algorithm for hyperbolic conservation laws using a combination of Fourier expansions and unstructured spectral/hp elements. The unstructured part of the algorithm is formulated using a discontinuous Galerkin approximation. The conservation properties of the unstructured algorithm using a variable polynomial order are examined and an orthogonal projection ...

Partial Differential Equations and the Finite Element Method provides a much–needed, clear, and systematic introduction to modern theory of partial differential equations (PDEs) and finite element methods (FEM). Both nodal and hierachic concepts of the FEM are examined. Reflecting the growing complexity and multiscale nature of current engineering and scientific problems, the author emphasizes ...

We analyze the consistency, stability, and convergence of an hp discontinuous Galerkin spectral element method. The analysis is carried out simultaneously for acoustic, elastic, coupled elastic–acoustic, and electromagnetic wave propagation. Our analytical results are developed for both conforming and non-conforming approximations on hexahedral meshes using either exact integration with Legendr...

Background: The association of HP and insulin resistance degree (IR) has not been evaluated in the diabetic patients so far. In this study, we evaluated the association between HP seropositivity and the homeostatic model assessment for insulin resistance (HOMA-IR) in diabetic patients. Methods: In this study, 211 diabetic patients admitted to the endocrinology clinic of Shahid Beheshti Hospita...

High-order accurate methods provide significant accuracy/cost benefits for well-resolved and geometrically simple scale-resolving turbulent flow simulations. However, the benefit on under-resolved unstructured grids complex industrial geometries is unclear. The purpose of this work to contribute understanding high-order schemes large-eddy simulations (LES) in practical applications. A crucial r...