Submission Guidelinesand Abstract Submission

Single or multiple exposures to mild stress at younger ages often have positive health beneficial effects throughout life, indicating that rescue systems turned on at a young age can be effective even in old age (e.g. Le Bourg 2011). This seems to be at variance with the notion of the so-called trade-offs that due to a limitation of resources it is impossible for an organism to increase all asp...

Hormesis has been defined as a dose-response relationship in which there is a stimulatory response at low doses, but an inhibitory response at high doses, resulting in a U- or inverted U-shaped dose response. To assess the proportion of studies satisfying criteria for evidence of hormesis, a database was created from published toxicological literature using rigorous a priori entry and evaluativ...

Hormesis is a specific type of nonmonotonic dose response whose occurrence has been documented across a broad range of biological models and diverse types of exposure. The effects that occur at various points along this curve can be interpreted as beneficial or detrimental, depending on the biological or ecologic context in which they occur. Because hormesis appears to be a relatively common ph...

Chlorophyll and carotenoid content (ChCar), lipid peroxidation (LP) and growth parameters (GP) in plants are often used for environmental pollution estimation. However, the nonmonotonic dose-response dependences (hormesis and paradoxical effects) of these indices are insufficiently explored following exposure to different pollutants. In this experiment, we studied nonmonotonic changes in ChCar,...

Hormesis has been defined as a dose-response relationship in which there is a stimulatory response at low doses but an inhibiting response at high doses, resulting in a Uor inverted U-shaped dose response. Until now, regulatory agencies have been reluctant to address this new insight or adjusted their routines for regulating such substances. Should regulators change their principles of decision...

Application of hormesis in aging research and interventions is becoming increasingly attractive and successful. The reason for this is the realization that mild stress-induced activation of one or more stress response (SR) pathways, and its consequent stimulation of repair mechanisms, is effective in reducing the age-related accumulation of molecular damage. For example, repeated heat stress-in...

We discuss the similarities and differences of two types of effects that occur at low but not high doses of chemicals: hormesis and stimulation by oestrogenic endocrine-disrupting chemicals or xenoestrogens. While hormesis is a general phenomenon evoked by many compounds, oestrogenic stimulation occurs for specific chemicals that disrupt actions of endogenous oestrogen. Both types of phenomena ...