Abstract Study question Can the use of a custom-designed and 3D printed microICSI™ device reduce degree oocyte invagination during intracytoplasmic sperm injection (ICSI)? Summary answer Invagination was significantly less in porcine oocytes when ICSI performed compared to conventional ICSI. What is known already difficult procedure for embryologists master, yet until recently, technically litt...

The advantages of the Seligson pipette in a clinical laboratory are well known (Seligson, 1957; Saifer, Gerstenfeld, and Zymaris, 1958). It is usually attached to a burette for adding diluent. Mather (1960) modifies the stopcock of the pipette and attaches it to an automatic burette. In this laboratory, two devices have proved satisfactory in over two years' continuous service. (1) A 0.35 ml. S...

Abstract Patch clamp recording of neurons is a labor-intensive and time-consuming procedure. Here, we demonstrate tool that fully automatically performs electrophysiological recordings in label-free tissue slices. The automation covers the detection cells images, calibration micropipette movement, approach to cell with pipette, formation whole-cell configuration, recording. based on deep learni...