The membrane fusion reaction promoted by the paramyxovirus simian virus 5 (SV5) and human parainfluenza virus type 3 (HPIV-3) fusion (F) proteins and hemagglutinin-neuraminidase (HN) proteins was characterized when the surface densities of F and HN were varied. Using a quantitative content mixing assay, it was found that the extent of SV5 F-mediated fusion was dependent on the surface density o...

AIM To establish a hypoxic environment for promoting osteogenesis in rat marrow stromal cells (MSCs) using osteogenic matrix cell sheets (OMCSs). METHODS Rat MSCs were cultured in osteogenic media under one of four varying oxygen conditions: Normoxia (21% O2) for 14 d (NN), normoxia for 7 d followed by hypoxia (5% O2) for 7 d (NH), hypoxia for 7 d followed by normoxia for 7 d (HN), or hypoxia...

Purpose. We seek to correlate conventional hydronephrosis (HN) grade and hydronephrosis index (HI). Methods. We examined 1207 hydronephrotic kidneys by ultrasound. HN was classified by Society of Fetal Urology guidelines. HN was then gauged using HI, a reproducible, standardized, and dimensionless measurement of renal area. We then calculated average HI for each HN grade. Results. Comparing HI ...

Global changes (e.g., warming and population growth) affect nutrient loadings temperatures, but global also results in more frequent extreme events, such as heat waves. Using data from the world’s longest-running shallow lake experimental mesocosm facility, we studied effects of different levels combined with varying which included a simulated 1-month summer wave (HW), on oxygen concentrations,...

OBJECTIVES/HYPOTHESIS Hemangiopericytomas (HPC) are tumors that arise from pericytes. Hemangiopericytomas of the head and neck are rare and occur both extracranially and intracranially. This study analyzes the demographic, clinicopathologic, treatment modalities, and survival characteristics of extracranial head and neck hemangiopericytomas (HN-HPC) and compares them to HPCs at other body sites...

Let h1, · · · , hn be positive integers. We study new sums m(h1, · · · , hn) = h1−1 ∑ r1=0 · · · hn−1 ∑ rn=0 min { r1 h1 , · · · , rn hn } and M(h1, · · · , hn) = h1−1 ∑ r1=0 · · · hn−1 ∑ rn=0 max { r1 h1 , · · · , rn hn } , the first of which times h1 · · ·hn is the number of lattice points in a pyramid of dimension n + 1. We show that m(h1, · · · , hn) (h1 − 1) · · · (hn − 1) = 1 + ∑ ∅6 =I⊆{1...

Mean-field spin glasses are families of random energy functions (Hamiltonians) on high-dimensional product spaces. In this paper, we consider the case Ising mixed p-spin models,; namely, Hamiltonians HN:ΣN→R Hamming hypercube ΣN={±1}N, which defined by property that {HN(σ)}σ∈ΣN is a centered Gaussian process with covariance E{HN(σ1)HN(σ2)} depending only scalar ⟨σ1,σ2⟩. The asymptotic value opt...

Zanamivir (4-guanidino-Neu5Ac2en [4-GU-DANA]) inhibits not only the neuraminidase activity but also the receptor interaction of the human parainfluenza virus type 3 (HPIV3) hemagglutinin-neuraminidase (HN), blocking receptor binding and subsequent fusion promotion. All activities of the HPIV3 variant ZM1 HN (T193I/I567V) are less sensitive to 4-GU-DANA's effects. The T193I mutation in HN confer...

Let Hn be the hyperbolic n-space with n ≥ 2. Suppose that Γ < Isom Hn is a discrete, torsion free subgroup and a is a point in the domain of discontinuity Ω(Γ). Let p be the projection map from Hn to the quotient manifold M = Hn/Γ. In this paper we prove that there exists an open neighborhood U of a in Hn ∪Ω(Γ) such that p is an isometry on U ∩ Hn.