background human immunodeficiency virus (hiv) testing strategy for tuberculosis (tb) patients in some high hiv incidence countries has been recommended based on interaction between hiv and tb. objectives the present study aimed to determine the prevalence of hiv infection among newly detected pulmonary tb patients. patients and methods in a cross sectional study,104 cases including 95 non injec...

OBJECTIVE To study the clinical symptoms associated with seroconversion for HIV-1 among misusers of intravenous drugs. DESIGN Case-control study in cohorts of drug misusers and homosexual men. SETTING Outpatient clinic, Municipal Health Service, Amsterdam. SUBJECTS Misusers of intravenous drugs from our prospective cohort who seroconverted for HIV. Controls were drug users positive for HI...

Human immunodeficiency virus infection / acquired immunodeficiency syndrome (HIV/AIDS) is a disease pertained to the human immune system. Given its crucial role in viral replication, HIV-1 protease (HIV-1 PR) is a prime therapeutic target in AIDS therapy. In this regard, the dynamic aspects of ligand-enzyme interactions may indicate an important role of conformational variability in HIV-1 PR in...

Background and Aims: Genotyping assay has been accepted as a guidance in the therapeutic management of Human Immunodeficiency virus 1 (HIV-1). But, it is not commonly used in our country due to its high running cost. The aim of this study is evaluate an in-house genotyping resistance test (GRT) for HIV-1. Methods: HIV-1 RNA of 20 samples were extracted from plasma and RT Nested- PCR was perform...

Post-natal HIV infection through breastfeeding remains a challenge in many low and middle-income countries, particularly due to non-availability of alternative infant feeding options the suboptimal Prevention Mother Child Transmission HIV-1 (PMTCT) cascade implementation monitoring. The PROMISE-EPI study aims address latter by identifying infected mothers during an almost never-missed visit for...

conclusions this study found that gbv-c infection has a high frequency among injecting drug users with hiv/hcv coinfection and hcv mono-infection in yunnan, china. in patients with chronic hepatitis c and hiv coinfection, gbv-c rna was associated with significantly lower alt and ast levels, suggesting a beneficial effect of gbv-c infection on chronic hepatitis c. results gbv-c rna was identifie...

background: beside various factors for producing diabetes, it seems that chronic hepatitis c, hiv/hcv co-infection, and anti-retroviral treatment especially including protease inhibitors may predispose to diabetes. this study conducted to determine prevalence of diabetes in hiv and hcv patients. methods: the registries of 150 hcv patients, 50 hiv patients and 90 hiv/hcv co-infected patients in ...

HIV-infected cells persist for decades in patients administered with antiretroviral therapy (ART). Meanwhile, an alarming surge drug-resistant HIV viruses has been occurring. Addressing these issues, we propose the application of photoimmunotherapy (PIT) against not only Env-expressing but also HIV. Previously, showed that a human anti-gp41 antibody (7B2) conjugated to cationic or anionic photo...

AMA Basimi P, Farrokhi M, Ghanbari Dehghan Manshadi SA, Naghib Baesi K. Drug-selective pressure effect on HIV integrase mutations in antiretroviral naïve and experienced patients. & AIDS Review. International Journal of HIV-Related Problems. 2023;22(2):99-103. doi:10.5114/hivar.2023.127727. APA Basimi, P., Farrokhi, M., Ghanbari, Manshadi, S. A., Naghib, Baesi, (2023). Problems, 22(2), 99-103. ...