Scoring the nuclear pleomorphism in histopathological images is a standard clinical practice for the diagnosis and prognosis of breast cancer. It relies highly on the experience of the pathologists. In a large hospital, one pathologist may have to evaluate more than a hundred cases per day, which is a very tedious and time-consuming task. Thus, it is necessary to develop an automatic system to ...

Purpose. To present initial experience with a novel biopsy method, the Essen biopsy forceps. Therefore, two patients with diagnostic suspicion of uveal melanoma underwent biopsy for histopathological confirmation. Case Presentation. Two patients presented with painless unilateral vision reduction. Ultrasound revealed the diagnostic suspicion of uveal melanoma. Therefore, biopsy with the Essen b...

Aim: Olanzapine has adverse effects on sexual dysfunction. There are a limited number of studies showing that it also causes structural changes in the reproductive system. This study aimed to examine L-Carnitine testicular damage caused by terms histopathological, sperm parameters, biochemical aspects. 
 Method: A total 48 adult Sprague-Dawley male rats were used our study. Rats divided in...

Histopathological image analysis plays an important role in the diagnosis and treatment of cholangiocarcinoma. This time-consuming complex process is currently performed manually by pathologists. To reduce burden on pathologists, this paper proposes a histopathological classification method for cholangiocarcinoma based spatial-channel feature fusion convolutional neural networks. Specifically, ...

BACKGROUND Breast cancer is the most common malignant neoplasm and the most common cause of death among women. The core needle biopsy is becoming a universal practice in diagnosing breast lesions suspected of malignancy. Unfortunately, breast core needle biopsies also bear the risk of having false-negative results. MATERIAL/METHODS 988 core needle breast biopsies were performed at the Maria S...

INTRODUCTION Hysteroscopy is considered the 'gold standard' procedure in assessing uterine pathology however it is more expensive and invasive method than ultrasonography. An alternative to the diagnostic hysteroscopy is sonohysterography. AIM To evaluate the usefulness of sonohysterography in detecting endometrial polyps in female patients diagnosed with infertility. MATERIAL AND METHODS W...

Any diagnostic method for detection of occult metastases in sentinel lymph node (SLN) could change postoperative therapeutic management. In this study, we attempted to evaluate the usefulness of immunohistochemical (IHC) studies for histopathological SLN examination and their impact on the diagnosis of metastatic lesions. Analyzed data concerned 1358 breast cancer patients referred for sentinel...

Objective: The aim of this study was to determine the accuracy of Fine needle aspiration cytology in detection of thyroid swellings in our ENT unit and to assess the correlation between preoperative cytodiagnosis and postoperative histopathological diagnosis.Study design: Cross sectional studyPlace & Duration of study: Department of ENTHead & Neck Surgery, Charak hospital, Pokhara, Nepal, from ...

Histopathology provides a rapid method to detect effects of irritants and pathogens in different organs and it can be considered as the indicator for abnormal condition for fish environment. The present study was initiated to record the histopathological lesions of gill and skin associated with external parasites in two common aquarium fish, Oscar (Astronotus ocellatus) and Discus (Symphysodon ...

OBJECTIVE To determine the protective effects of vitamin E against the damage inflicted by reactive oxygen species during toluene induced brain injury in rats using histopathological, biochemical, and behavioral parameters. METHODS Twenty-eight Wistar albino male rats were studied at Hacettepe University Faculty of Medicine Laboratories and Gazi University Faculty of Medicine Metabolism Labor...