BACKGROUND AND PURPOSE Primary and dynamically maintained periprosthetic bone formation is essential for osseointegration of hip implants to host bone. Bone morphogenetic proteins (BMPs) play a role in osteoinductive bone formation. We hypothesized that there is an increased local synthesis of BMPs in the synovial membrane-like interface around aseptically loosened total hip replacement (THR) i...

Cementless acetabular fixation has demonstrated superior long-term durability in total hip replacement, but most series have studied implants with porous metal surfaces. We retrospectively evaluated the results of 100 consecutive patients undergoing total hip replacement where a non-porous Allofit component was used for primary press-fit fixation. This implant is titanium alloy, grit-blasted, w...

BACKGROUND There were at least 31,171 metal-on-metal (MoM) hip implants in the UK between 2003 and 2011. Some of these were subject to failure and widescale recalls and revisions followed. METHOD This is a presentation of ten cases (mean age 60 years) where we evaluated neuropsychiatric morbidity following metal-on-metal hip implant failure and revision. Implants were ASR total hip replacemen...

The disrupted function of the hip joint can be restored by means of total hip arthroplasty (i.e. reconstructive surgery of the joint) THA. This is a widely used medical strategy with high succes rates, world wide [1,2]. Among the failure scenarios of THA, aseptic loosening represents the main reason for revision of cemented hip implants [3]. Studies have shown that the two most frequent ways fo...

This is a review of the hip arthroplasty era. We concentrate on new metal bearings, surface replacements, and the lessons not learned, and we highlight recent reports on malignancies and joint implants. A low incidence of blood malignancies has been found in bone marrow taken at prosthetic surgery. The incidence is increased after replacement with knee implants that release very low systemic le...

Introduction: Metal-on-metal (MOM) hip resurfacing implants were predicted to be suitable for young, active patients (1). However, there are indications that the MOM-implants fail more frequently than traditional implants (2), possibly caused by an aseptic lymphocytic vasculitis-associated lesion in the tissues surrounding the implant (3). The diagnosis of these lesions by MRI would be facilita...

Most tuberculosis infections of the musculoskeletal system occur in the spine, hip or knee with Hip tuberculosis (TB) constituting 15%-20%. Highest rates of the tuberculosis cases in Indonesia occur in Papua. Neglected cases or delayed treatment can make management challenging. We present a 47 years old Papuan man who presented with progressive destructive TB of the hip due to lack of resources...

This study investigates the adhesion capacity of a polyglycolic acid- (PGA-) hyaluronan scaffold with a structural modification based on a planar polymer (PM) surface in a cadaver cartilage defect model. Two cadaver specimens were used to serially test multiple chondral matrices. In a cadaver hip model, cell free polymer-based cartilage implants with a planar bioinspired PM surface (PGA-PM-scaf...

In recent years, various uncemented proximal metaphyseal hip stems were introduced for younger patients as a bone preserving strategy. Initial osteodensitometric analyses of the surrounding bone of short stems indicate an increase of bone mass with secondary bone ingrowth fixation as a predictor of long-term survival of these types of implants. We report the outcome of 151 modular Metha short h...