نتایج جستجو برای: high throughput screening

تعداد نتایج: 2256107  

Journal: :ASSAY and Drug Development Technologies 2008

Journal: :Biochip Journal 2023

Abstract Although surface-enhanced Raman spectroscopy (SERS) is a powerful analytical technique with unbeaten sensitivity, the capabilities of SERS have been not fully utilized in screening applications because throughput spectrum detection by conventional instruments has restricted due to their single-point measurement manners. Hence, this paper presents development high system that employs fi...

Journal: :Journal of chemical information and modeling 2012
Gregory A. Bakken Andrew Bell Markus Boehm Jeremy R. Everett Rosalia Gonzales David Hepworth Jacquelyn L. Klug-McLeod Jeremy Lanfear Jens Loesel John Mathias Terence P. Wood

High Throughput Screening (HTS) is a successful strategy for finding hits and leads that have the opportunity to be converted into drugs. In this paper we highlight novel computational methods used to select compounds to build a new screening file at Pfizer and the analytical methods we used to assess their quality. We also introduce the novel concept of molecular redundancy to help decide on t...

Journal: :Acta Crystallographica Section A Foundations of Crystallography 2002

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