Introduction: Microdosimetry is a fundamental method that studies the nature of energy transfer in micron volumes in the particular biological cells. In a biological target, the amount of ionization does not indicate the magnitude of biological radiation-induced damage. However, the severity of biological harm depends strongly on the amount of the linear energy transfer along t...

Dose distribution evaluation in oncological radiotherapy treatments is an outstanding problem that requires sophisticated computing technologies to optimize the clinical results (i.e. increase the dose to the tumour and reduce the dose to the healthy tissues). Nowdays, dose calculation algorithms based on the Monte Carlo method are generally regarded as the most accurate tools for radiotherapy....

The properties of a new scintillation detector system for use in dosimetry of high-energy beams in radiotherapy have been measured. The most important properties of these detectors are their hgh spatial resolution and their nearly water-equivalence. Measurements have shown that they have excellent reproducibility and stability, and a linear response versus dose-rate. It is also shown that they ...

Some recent studies in Italy have focused on the possibility of exploiting clinical high energy electron linear accelerators, normally used in photon radiotherapy, as photo-neutrons source for in-hospital neutron medical applications. In-Hospital photo-neutron radiotherapy extends the possibilities of Boron Neutron Capture Therapy (BNCT) to external treatment of diffused tumors when other metho...

background depending on the cause, 40-90% of every deep dermis insult ends up in scar formation. several modalities have been suggested as a treatment but a high rate of recurrence is reported in most of those interventions. high dose radiotherapy has been shown to be effective in reducing the recurrence rate. this study tried to determine the effectiveness of low dose rate radiotherapy followi...

introduction intensity-modulated radiotherapy (imrt) is becoming an increasingly routine treatment method. imrt can be delivered by use of conventional multileaf collimators (mlcs) and/or physical compensators. one of the most important factors in selecting an appropriate imrt technique is integral dose. integral dose is equal to the mean energy deposited in the total irradiated volume of the p...

MRI is often used in tumor localization for radiotherapy treatment planning, with gadolinium (Gd)-containing materials often introduced as a contrast agent. Motexafin gadolinium is a novel radiosensitizer currently being studied in clinical trials. The nanoparticle technologies can target tumors with high concentration of high-Z materials. This Monte Carlo study is the first detailed quantitati...

BACKGROUND AND PURPOSE One of the newer audit modalities operated by the International Atomic Energy Agency (IAEA) involves audits of treatment planning systems (TPS) in radiotherapy. The main focus of the audit is the dosimetry verification of the delivery of a radiation treatment plan for three-dimensional (3D) conformal radiotherapy using high energy photon beams. The audit has been carried ...