INTRODUCTION In attempting to improve local tumor control by higher doses of radiation, there has been a resurgence of interest in the implementation of brachytherapy in the management of primary and recurrent cancers of the nasopharynx. Brachytherapy with its steep dose fall-off is of particular interest because of the proximity of critical dose limiting structures. Recent developments in brac...

AIM To assess clinical outcomes of patients treated with a high-dose rate brachytherapy boost for anal canal cancer (ACC). METHODS From August 2005 to February 2013, 28 patients presenting an ACC treated by split-course external beam radiotherapy (EBRT) and HDR brachytherapy with or without chemotherapy in a French regional cancer center in Nice were retrospectively analyzed. RESULTS Median...

BACKGROUND To retrospectively evaluate the outcome of patients with inoperable non-small-cell lung cancer treated with primary external beam radiotherapy combined with high-dose-rate endobronchial brachytherapy boost. PATIENTS AND METHODS Between 1988 and 2005, 35 patients with non-small-cell lung cancer (stage I-III) ineligible for surgical resection and/or chemotherapy, were primarily treat...

As most local recurrence after breast-conserving treatment occurs within 2 cm around the lumpectomy cavity, wide-volume partial breast rather than whole breast irradiation has been actively investigated with a view to decreasing radiation toxicities. Replacing external beam radiotherapy by wide-volume interstitial brachytherapy offers the advantages of more accurate treatment volume coverage an...

PURPOSE The objective was to determine whether optically stimulated luminescent dosimeters (OSLDs) were appropriate for in vivo measurements in high dose rate brachytherapy. In order to make this distinction, three dosimetric characteristics were tested: dose linearity, dose rate dependence, and angular dependence. The Landauer nanoDot™ OSLDs were chosen due to their popularity and their availa...