The association of hidradenitis suppurativa with Down’s syndrome has long been suspected. First proposed in 1992 by Spanish authors [1], the connection came under the spotlight again more recently in a correspondence article published in the British Journal of Dermatology [2]. Including the five cases given in that article, there have only been ten such cases recorded worldwide to date, but the...

Streptococcus milleri was isolated from the active lesions of three patients with perineal hidradenitis suppurativa. In each patient, elimination of this organism by appropriate antibiotic therapy was accompanied by marked clinical improvement.

In this study, twenty cases of severe hidradenitis suppurativa are reported, mainly in non-white people and in axillary areas. Wide surgical excision has offered good results, although relapses have occurred at variable intervals in the follow-up period.

Host-defence defects in hidradenitis suppurativa patients have been suspected, but not proven. Activated neutrophils can destroy the surrounding tissues by a release of reactive oxygen species and active proteases. Peripheral neutrophils from 15 female patients (mean age 46, range 27-57 years) in an inactive state of their hidradenitis suppurativa, were studied and compared with 15 age-matched ...

BACKGROUND Hidradenitis suppurativa is a chronic inflammatory disease of the cutis with furuncles, fistulas, and abscesses. The disease is mostly located in groin and axilla. As conservative treatment can usually not prevent recurrence, surgical treatment is the method of choice. METHODS We report on 20 patients with axillary hidradenitis suppurativa. The inflammatory region was excised in a ...

BACKGROUND Determining treatment response for patients with hidradenitis suppurativa (HS) can be challenging due to limitations of current disease activity evaluations. OBJECTIVE Evaluate the novel, validated endpoint, Hidradenitis Suppurativa Clinical Response (HiSCR) and its utility as an outcome measure. METHODS Patients with baseline total abscess and inflammatory nodule count (AN count...

In order to establish the possible role of androgen in the development of hidradenitis suppurativa the symptomatology of the disease was studied in a group of 70 female patients. The results were compared with those obtained from an age-matched control group of healthy women. The incidence of women with signs of androgenization in the two groups did not differ significantly. The only significan...

The hidradenitis suppurativa is a chronic debilitating inflammatory disease whose etiology is not fully understood. We conducted a pilot case-control study matched by sex and age with other dermatological patients to analyze possible risk factors associated with this disease. We included 15 cases and 45 controls, 67% were women. Bivariate and multivariate logistic regression analysis identified...