R. P. Goodrich and co-workers, 1989 have reported that red blood cells (RBCs) can be preserved in the dry state by addition of mixtures of hydroxyethyl starch (HES) and glucose (59,60). In this thesis work we tried to investigate the effect of HES alone on the viability, functionality and oxidative state of red blood cells after freeze thaw stress. Here we prepared eight formulations having var...

We report the histopathologic and dermatologic manifestations of eight patients with hypereosinophilic syndrome (HES). Skin lesions occurred in eight patients (53%) in a group of 15 patients with HES, and were generally of two types: (1) erythematous pruritic papules and nodules, or (2) urticaria and angioedema. As HES was treated with appropriate therapy, the skin lesions improved. Skin erupti...

The objective of this investigation was to study the gastrointestinal and hepatic involvement in hypereosinophilic syndrome (HES). Gastrointestinal or hepatic involvement is estimated to affect up to one-third of patients with HES, although most of the clinical evidence has been derived from case reports. In literature, HES presenting with hepatitis and jaundice with subsequent development of c...

Volume therapy is a standard procedure in daily perioperative care, and there is an ongoing discussion about the benefits of colloid resuscitation with hydroxyethylstarch (HES). In sepsis HES should be avoided due to a higher risk for acute kidney injury (AKI). Results of the usage of HES in patients without sepsis are controversial. Therefore we conducted an animal study to evaluate the impact...

Hydroxyethyl starch (HES) solution is an effective colloidal infusion solution in humans for treatment of hypovolaemic shock, but it has not been compared with fluids currently available for use in horses. On the basis of plasma-expanding effect of HES in normal horses, a 10% medium-molecular 200/0.5 solution of HES was subsequently tested in hypovolaemic horses. Six normal horses were given fi...

As the electricity sector evolves, and as all energy types (thermal, electric, chemical, etc.) become more coupled, there has been increased interest to develop deploy hybrid systems (HES). This work focuses on fully integrated HES, where are multiple sources products, often coupled through a storage buffer. A significant amount of available literature this describes technology pathways for HES...

The purpose of this study was to explore the potential formulating hesperetin into an ophthalmic solution with dipotassium glycyrrhizinate (DG) as a micelle nanocarrier. A DG-based encapsulating (DG-Hes) developed and its in vitro/in vivo characterizations were evaluated. optimal formulation featured DG/hesperetin (Hes) weight ratio 12:1 encapsulation efficiency 90.4 ± 1.7%; optimized DG-Hes ch...

BACKGROUND The chemical inertness of hydroxyethyl starch (HES) might cause interferences of the colloid with a variety of laboratory tests. We aimed to evaluate potential influences of HES 130/0.4, the newest HES type, on several common hematology and clinical chemistry parameters. METHODS AND RESULTS A convenient sample of 25 patients scheduled for rheological therapy with 500 mL 6% HES 130/...

The cell-substrate interface plays a key role in the regulation of cell behaviour. Defining the properties of this interface is particularly important for human embryonic stem (hES) cell culture, because changes in this environment can regulate hES cell differentiation. It has been established that fibronectin-coated surfaces can promote the attachment, growth and maintenance of the undifferent...

BACKGROUND Hydroxyethyl starch (HES) solutions alter blood coagulation, mainly platelet function and fibrinogen polymerization. Haemostasis can also be impaired by dilutional-hyperchloraemic acidosis induced by the HES carrier solution. We hypothesized that a saline-based tetrastarch carrier solution impairs parameters of blood coagulation more than a balanced carrier solution. METHODS The st...