We report herein a rare instance in which a patient presented with a hemorrhagic cerebral metastasis as the initial manifestation of a hepatocellular carcinoma (HCC). A few cases of cerebral metastasis from HCC have been reported in the literature, mainly from eastern countries. This is the first report from South America of a cerebral metastasis from hepatocellular carcinoma.

Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide. Understanding the pathogenesis HCC has significantly improved in past few years due to advances genetics, molecular biology and pathology. Several subtypes have been identified with different backgrounds outcomes, leading possible changes disease management challenging role imaging. Indeed, despite its pivotal di...

The fibrolamellar variant of hepatocellular carcinoma (HCC) is an uncommon tumour with distinctive clinical and histological features. Although the first case of fibrolamellar hepatocellular carcinoma (FI-HCC) was described by Edmondson in 1956, and later confirmed in five patients by Peters, the majority of reports followed those of Berman et al. and Craig et al. A case of FI-HCC, which is rar...

As one of the most common malignancies worldwide, Hepatocellular carcinoma (HCC) has been treated by Sorafenib, which is first approved target drug FDA for advanced HCC. However, resistance obstacles to its application. a typical characteristic solid tumors, hypoxia become key cause chemotherapy and radiotherapy. It important elucidate underlying mechanisms Sorafenib under hypoxia. In this stud...

Treatment for hepatocellular carcinoma (HCC) has been challenging as most patients present with late, advanced disease, where curative options are limited. For years, locoregional therapy (LRT) the first-line intermediate-stage HCC and sorafenib HCC. However, these treatments often palliative since they plagued by tumor recurrence or progression. Therefore, there is growing interest in combined...

Primary liver cancer is uncommon and is generally classified as hepatocellular carcinoma (HCC), bile duct carcinoma, neuroendocrine (or carcinoid) tumor, and mesenchymal tumor (sarcoma). Here we describe the gross and histopathology characteristics of a rare HCC in a captive Arabian sand cat (Felis margarita harrisoni) held at Al Ain Zoo, United Arab Emirates. The description of this case in th...

Abstract Multicentric fibrolamellar hepatocellular carcinoma has not been reported yet in the world as of our knowledge. A Medline search for term “multicentric HCC” did return any results. To knowledge, this is first case report multi-centric (HCC). We present a 22-year-old male patient who had complaints epigastric pain 1 month. His general physical examinations were normal. Computed tomograp...

Anatomical resection (AR) has been reported to achieve better long-term outcomes than non-anatomical for the treatment of hepatocellular carcinoma (HCC). The surgical feasibility and oncological significance laparoscopic AR (LAR), especially “subsegment resection”, “cone unit repeat LAR HCC, remain unproven. We present a 67-year-old patient with alcoholic liver cirrhosis HCC who underwent full ...

Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide. There is growing evidence for a chemopreventive role of nutrition in the development of HCC in at risk populations. Bibliographical searches were performed in PubMed for the terms 'nutrition and hepatocellular carcinoma', 'nutrition and liver cancer', 'nutrition and hepatic cancer', 'diet and hepatocellular...

XRCC1-399 allele polymorphisms have been reported to be associated with susceptibility to hepatocellular carcinoma (HCC), but the conclusions of the various studies have been inconsistent. We conducted a meta-analysis of available studies to determine whether XRCC1-399 alleles influence susceptibility to hepatocellular carcinoma. We searched English-language databases, including PubMed, Medline...