REFERENCES 1 Calabrese LH, Zein N, Vassilopoulos D. Safety of antitumour necrosis factor (anti-TNF) therapy in patients with chronic viral infections: hepatitis C, hepatitis B, and HIV infection. Ann Rheum Dis 2004;63:ii18–24. 2 Brunasso AM, Puntoni M, Gulia A, et al. Safety of anti-tumour necrosis factor agents in patients with chronic hepatitis C infection: a systematic review. Rheumatology (...

background: approximately 600,000 deaths occur every year as a result of the acute and chronic consequences of hepatitis b virus infection. ten different hepatitis b virus genotypes have been identified with distinct geographical distributions. different clinical outcomes, including the rate of mutations, development of hepatocellular carcinoma, chronicity, response to treatment, transplantatio...

background and aims: many studies have provided evidence for the role of hepatitis b and c viruses in the development of liver cancer. although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with hbv and hcv. this study was performed to determine the frequency of hbv/hcv-coinfection in mashhad, north-east of iran. mat...

background: raw sewage contains various pathogenic organisms including bacteria, viruses, fungus, worms and protozoa. workers at wastewater treatment plants (wwtps) are exposed to these organisms as well as to h2s gas causing many health hazards. objectives: to assess some work-related health effects among wwtps workers with special emphasis on the most common infections as well as cardiopulmon...

OBJECTIVE To determine whether prolonged infection with hepatitis B virus is associated with a lower blood cholesterol concentration. DESIGN Cross sectional study. SETTING 81 villages in rural China with a high prevalence of chronic infection with hepatitis B virus. SUBJECTS 1556 apparently healthy men aged 35-64 years, randomly selected. MAIN OUTCOME MEASURES Hepatitis B virus carrier ...

conclusions overall, we found that obi was rare, but that the prevalence of obi was slightly higher in jiangsu than in other areas of china. methods all donor samples were routinely screened by double enzyme-linked immunosorbent assay (elisa) for hepatitis c virus (hcv), hepatitis b virus (hbv), human immunodeficiency virus (hiv), treponema pallidum (tp), and alanine aminotransferase (alt). sin...

BACKGROUND Viral hepatitis with various forms of acute and chronic liver disease as potential and ultimately fatal sequelae presents a public health problem worldwide. METHODS Recent published reports on the global epidemiology and prophylaxis of viral hepatitis were reviewed. RESULTS With the advances in novel technologies, eight distinct types of hepatitis virus have been described: Hepat...

The prevalence of viral hepatitis is high and remains a serious public health challenge throughout the world. New molecular biology techniques provided a better understanding of the viruses over the last decades. Novel therapeutic options seem to be promising but preventing measures including donor screening, immunization against hepatitis A virus (HAV) and hepatitis B virus (HBV), universal us...

Hepatitis outbreaks in hemodialysis (HD) patients and staff were reported in the late 1960s, and a number of hepatotropic viruses transmitted by blood and other body fluids have been identified. Hepatitis B virus (HBV) was the first significant hepatotropic virus to be identified in HD centers. HBV infection has been effectively controlled by active vaccination, screening of blood donors, the u...

BACKGROUND AND PURPOSE Major hepatotropic viruses continue to be important causes of acute viral hepatitis in developing countries. This work was carried out to detect the seroprevalence of hepatitis E virus (HEV) markers in children with acute viral hepatitis due to hepatotropic viruses (A, B and C) and non-A, non-B, non-C acute hepatitis, and to ascertain the influence of HEV superinfection i...