context several risk factors play the role in the development of hepatocellular carcinoma (hcc) from which chronic hepatitis b and c infections are the most important ones. dna integration of hepatitis viruses alters the function of critical genes promoting malignant transformation of virus-infected liver cells. evidence acquisition there are remarkable geographic differences in prevalence of c...

conclusions despite the presence of vast oxidative stress in hepatitis b, antioxidant therapy is not always effective as a treatment strategy, especially considering that antioxidants can act as “double-edged swords” or antioxidants; if not used at the right time or place or in the right combination, these substances can easily become pro-oxidants. therefore, several studies will be needed to d...

conclusions our data show that not only general health and physical activity were preserved but also health perception may be better among hd patients with viral hepatitis. background there are surprisingly a few studies that evaluate the impact of chronic viral hepatitis, which is common in hd (hemodialysis) patients, on hrqol (health related quality of life). objectives we conducted a study t...

background: in patients with hepatitis b and c, environmental factors such as smoking and alcohol can cause liver fibrosis progression. but opium effects on liver fibrosis progression are not clear. this study was designed to assess the relationship of opium user and liver fibrosis progression. methods: in this case-control study, sixty patients in hepatitis b group and sixty patients in hepati...

Background Infants of diabetic mothers (IDMs) have significantly greater risk for spontaneous abortion, stillbirth, congenital malformations and perinatal mortality and morbidity but whether maternal DM affects the neonatal innate immune system is unknown. We aimed to assess the immune response of infants of diabetic mothers (IDMs) with non-gestational DM for Hepatitis B vaccine and to compare ...

Background: SEN virus (SENV) is the latest virus proposed as a cause of unknown hepatitis cases. Among nine detected genotypes of the virus, genotypes D and H are more frequent in hepatitis cases of unknown origin. The aim of this study was to determine the frequency of SENV-D and SENV-H genotypes in the sera of healthy individuals and hepatitis B and C patients. Methods: Totally, 200 serum sam...

Background: To promote general health in patients with hepatitis, it is vital to develop effective interventions to improve the lifestyle of these patients. The present study aimed to investigate the effectiveness of group cognitive-behavioral therapy (CBT) on the lifestyle of patients with hepatitis B. Methods: This was a quasi-experimental study with pretest-posttest control group design. A ...

Background & Aims: Hepatitis B infection is a global health problem. Hepatitis B virus can escape from the innate immune system, however adaptive immune system mainly acts against it. Transforming growth factor (TGF-) has three isoforms in mammals. Several studies have recently shown that TGF-1 suppresses replication of hepatitis B virus. Moreover, high expression of this factor is effective in...