We present a 74-year-old woman who developed a portal vein thrombosis following an elective total knee replacement. She had atrial fibrillation for which she was taking warfarin for anticoagulation. Seven days prior to surgery, she was instructed to discontinue warfarin and replace it with prophylactic low-molecular-weight heparin. On postoperative day 1, routine blood tests revealed deranged h...

Inflammatory bowel diseases are associated with an increased risk of vascular complications. The most important are arterial and venous thromboembolisms, which are considered as specific extraintestinal manifestations of inflammatory bowel diseases. Among venous thromboembolism events, portal vein thrombosis has been described in inflammatory bowel diseases. We report three cases of portal vein...

Dear Editor, Valla and his team pioneered the thorough search for latent myeloproliferative neoplasms (MPN) in patients with splanchnic thrombosis. They noticed that “primary myeloproliferative disorder, often without peripheral blood changes, is a major cause of hepatic vein thrombosis”. Valla provided precious guidelines for anticoagulant therapy suggesting to start anticoagulation as early a...

background all conditions that interfere with blood flow at any level within the portal system can lead to portal hypertension. for better management of this disorder, it is important to determine the underlying cause. in previ­ous studies, extra-hepatic disorders have been reported as the main cause of portal hypertension in children. in this study, we investigate the under­lying causes of por...

background: venous thromboembolism, which comprises deep vein thrombosis and pulmonary embolism and is a significant cause of morbidity and mortality among patients with cancer. the aim of the present study was to report a rare presentation of arterial thrombosis after venous thrombosis in a patient with gastric cancer. report of the case: a 45 year-old female patient with locally advanced gast...

Diffuse thrombosis of the entire portal system (PVT) and cavernomatous transformation of the portal vein (CTPV) represents a demanding challenge in liver transplantation. We present the case of a patient with nodular regenerative hyperplasia and recurrent episodes of type B hepatic encephalopathy concomitant with PVT as well as CTPV, successfully treated with orthotopic liver transplantation. T...

Portal vein thrombosis (PVT) is a rare form of venous thrombosis that affects the hepatic portal vein flow, which can lead to portal hypertension. Treatment of PVT includes anticoagulants, thrombolysis, insertion of shunts, bypass surgery, and liver transplantation. Single anticoagulation therapy is not regarded as a curative treatment but can be associated with a reduction in new thrombotic ep...