In understanding mechanisms of liver repopulation with transplanted hepatocytes, we studied the consequences of hepatic polyploidization in the two-thirds partial hepatectomy model of liver regeneration. Liver repopulation studies using genetically marked rodent hepatocytes showed that the number of previously transplanted hepatocytes did not increase in the liver with subsequential partial hep...

Presenter: Federico Aucejo MD | Cleveland Clinic Foundation Background: The early series of laparoscopic liver resections (LLR) were often non-anatomic minor resections, but recent surgical/instrumental advantages enable surgeons to apply LLR anatomical major resection. Although has been established in some Asian/European experienced centers, the pure is still not widely accepted US. In our ins...

Long-term survival in children with primary hepatic malignancies can not be expected without complete tumor resection. In the last ten years we have treated 21 children with hepatocellular carcinoma (HCC) and 21 children with hepatoblastoma (HEP), with tumor extirpation our surgical goal. Operative treatment included partial hepatectomy ([PH] 20), either primary (10) or delayed (following chemo...

PURPOSE To investigate the influence of partial colectomy associated with hepatectomy on the biodistribution of the (99m)Tc-phytate, on metabolic parameters, as well as labeling and morphology of red blood cells. METHODS Wistar rats were distributed into three groups (each with six), nominated as colectomy, colectomy+hepatectomy and sham. In the 30(th) postoperative day all rats were injected...

Flow cytometric analysis of asialoglycoprotein receptor (ASGPR) levels on the surface of hepatocytes, which were obtained from the liver specimens of patients that received hepatectomy, were used as predictors of liver dysfunction after major hepatectomy for primary hepatocellular carcinoma (HCC) in Chinese patients, based on our previous study which confirmed the value of ASGPR levels on the s...

OBJECTIVE To evaluate the efficacy of intraoperative (IO) ultrasonography (US) as compared with other imaging modalities on the primary and repeated hepatectomies for hepatocellular carcinoma. DESIGN Retrospective study. SETTING University hospital. PATIENTS From January 6, 1995, to December 26, 2002, 430 patients underwent 555 operations for hepatocellular carcinoma. MAIN OUTCOME MEASU...

BACKGROUND The optimal treatments for gastric cancer with liver metastases (GCLM) remain controversial. This study aimed to evaluate the efficacy of hepatectomy, RFA and TACE as local treatments for GCLM. METHODS From 2001 to 2015, 119 consecutive patients who received multidisciplinary treatments based on curative gastrectomy and local treatments (hepatectomy, RFA and TACE) for liver metasta...

One of the major reasons for unresectability liver is that remnant volume insufficient to support postoperative function. Post-hepatectomy insufficiency one most serious complications in patients undergoing hepatic resection. Preoperative portal vein embolization performed with aim inducing hypertrophy future and thought reduce risk after hepatectomy. We, interventional radiologists, are requir...

of major hepatectomy for hepatocellular carcinoma associated with cirrhosis. Objective: To deWne the safety of major hepatectomy for hepatocellular carcinoma (HCC) associated with cirrhosis and the selection criteria for surgery in terms of hospital mortality.

The effect of partial (70 %) hepatectomy on phosphatidylcholine (PC) synthesis in rat liver was investigated during the first 4 post-operative days. Between 4 and 96 h after partial hepatectomy, the mass of PC increased from 30% to 80% of sham-operation values, being comparable with the restoration of total liver mass after partial hepatectomy. Relative to control (sham-operation), the incorpor...