Background: The human T-cell lymphotropic virus type I is the first retrovirus idenfied in humans. The virus has been associated with adult T-cell leukemia/lymphoma, human T-lymphotropic virus type I, myelopathy/tropical spasc paraparesis, uveis, arthris, pulmonary lymphocyc alveolis, keratoconjuncvis sicca, and infecous dermas. Human T-lymphotropic virus type Iis endemic in Japan...

background: hepatitis g virus (gbv-c) is a single strand rnapositive virus and is a member of flaviviridae family. infection with the virus is prevalent add has worldwide distribution. accurate diagnosis of the virus is very important, because of co-infection with other important viruses like hcv, hbv and hiv, it may influence on pathogenesis, disease progression and response to viral therapy. ...

background and objective: although transfusion therapy has lead to great improvement in longevity for hemophiliacs, but there have been tragic setbacks especially from transmission of human immunodeficiency virus (hiv) and hepatitis c virus (hcv) .hiv was reported to increase the rate of hcv-related liver failure by 4.2 times. in this study, we aimed to determine the seroprevalence of hiv and h...

context hepatitis b virus (hbv) and hepatitis c virus (hcv) infections constitute a major global health problem. about 60,000 and 350,000 deaths occur as the results of hbv and hcv infections, respectively. chronic hepatitis b and c infections are leading causes of cirrhosis and hepatocellular carcinoma (hcc) which are considered as the third cancer-associated cause of deaths worldwide. iran su...

conclusions the most frequent subtypes of hcv in iran were 1a, 3a and 1b, respectively. this frequency differed in various provinces of iran and fluctuated with time. it is important to determine the distribution of hcv genotypes in different geographical areas and its trend with time for epidemiological and patients’ management purposes. objectives the aim of this study was to estimate the ove...

background hepatitis c virus (hcv) is the major cause of chronic liver disease. hcv is a single stranded positive sense rna of approximately 9.6 kb. because of high conservativeness of 5΄untranslated region of hcv genome, it is widely used for virus genotyping. different methods are used for the virus genotyping, but all involve some difficulties. objectives the aim of the present study was to ...

conclusions this study can serve as a fundamental experiment for the construction of a ns3/ns4a eukaryotic expression vector and its expression in mammalian cells. further research is underway to evaluate the fragment immunogenicity in lab animal models. results the results showed that the fragment was successfully amplified and cloned into a eukaryotic expression vector. sequencing and enzyme ...

the patient was infected with hcv subtype 6a. prior to this case, there have been no previous reports on the isolation of this genotype/subtype from any other iranian patient. previous epidemiological studies provide valuable information about the distribution patterns of different hcv genotypes. however, infection with genotypes other than common ones should be flagged by specialists and diagn...