By HAL CRAWFORD, B.SC., MARIE CUTBUSH, B.Sc., AND P. L. M0LLI50N, M.D., M.R.C.P. T HE DIAGNOSIS of hemolytic disease of the newborn is made by demonstrating incompatibility between the mother’s serum and the infant’s red cells, associated w-ith signs of red cell destruction in the infant . When the disease is due to anti-Rh itis not uncommoui to find evidence of serologic incompatibility, inclu...

By HAL CRAWFORD, B.SC., MARIE CUTBUSH, B.Sc., AND P. L. M0LLI50N, M.D., M.R.C.P. T HE DIAGNOSIS of hemolytic disease of the newborn is made by demonstrating incompatibility between the mother’s serum and the infant’s red cells, associated w-ith signs of red cell destruction in the infant . When the disease is due to anti-Rh itis not uncommoui to find evidence of serologic incompatibility, inclu...

Intruduction: There is a growing concern about an increasing bilirubin-induced neurological dysfunction (BIND) in healthy term neonates with no evidence of hemolytic disease or other risk factors. This study was done to determine the incidence of BIND in otherwise healthy, breast-fed newborn term infants without hemolysis who underwent exchange transfusion.   Methods: This study was conducted i...

Abstract Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rh system antibodies is a significant cause of hemolytic disease the fetus and newborn. Here, we report rare case severe perinatal associated with maternal antibody e antigen. In addition anemia, infant developed hyperbilirubinemia. Resolution infant’s anemia hyperbilirubinemia occurred after treatment photo...

"Common red blood cell disorders encountered in the normal newborn nursery include hemolytic disease of the newborn and resultant hyperbilirubinemia, anemia, and polycythemia. A less frequent clinically relevant hematologic issue in newborns to be covered herein is thrombocytopenia."

background and aims: glucose-6-phosphate dehydrogenase (g6pd) is the first enzyme in the route of pentose phosphate metabolism. this route fulfills an effective role in removing oxidant metabolites. deficiency of this enzyme causes decline in energy regeneration of red blood cells and hemolysis. in this study, application of fluorescence staining method in diagnosing the frequency of g6pd defic...