We describe a 42-year-old man presenting to the emergency department with cardiogenic shock. He had a prior history of acute pulmonary embolism (PE), and had been on anticoagulation for 2 years. Although computed tomographic pulmonary angiography performed at the emergency department showed no change in the extent of PE and did not support a role of surgical treatment, pulmonary embolectomy was...

The pathologically hypertrophied and failing heart is a battlefield in a war that would make even George Lucas proud. On the one side, you have hemodynamic, neurohormonal, morphological, and cellular/molecular dark forces urging the ventricle toward decompensation and ultimate demise. On the other, Jedi signaling cascades try valiantly to stave off the impending disaster. Alas, unlike the movie...

background there have been many concerns about alteration in hemodynamic parameters within and shortly after endotracheal intubation (eti) in patients scheduled for elective coronary artery bypass grafting (cabg). objectives we compared the attenuation effect of magnesium sulfate and lidocaine on hemodynamic responses after eti, in patients undergoing cabg. patients and methods in this randomiz...

From the embryonic state to the end of life, the elements of the circulatory system are exposed to hemodynamic forces associated with the circulation of blood. Various levels of intraluminal (transmural) pressure and wall shear stress represent the natural environment for the tissues of the vascular wall. Physiological or pathological changes in the level of these forces elicit active responses...

The hemodynamic effects of oral hydralazine were investigated in ten patients (nine in NYHA Class IV and one in Class III) with chronic refractory heart failure. With hemodynamic monitoring, adequate oral doses of hydralazine (50 or 75 mg) were determined and then administered every six hours. Hemodynamics were determined at 2-3, 6-8 and 24 hours on hydralazine therapy. Arterial pressure decrea...

Hemodynamics in sepsis change as sepsis develops. Initial hemodynamics of sepsis often are much different from later stages of sepsis, shifting from low cardiac output states to high cardiac output states. Tissue oxygenation also changes with initial mixed venous oxyhemoglobin (Svo2) or central venous oxyhemoglobin (Scvo2) levels below normal, with later stages reflecting high values. These cha...

Recent interest in functional hemodynamic monitoring for the bedside assessment of cardiovascular insufficiency has heightened. Functional hemodynamic monitoring is the assessment of the dynamic interactions of hemodynamic variables in response to a defined perturbation. Accordingly, fluid responsiveness can be predicted in a quantities fashion by measuring as arterial pulse pressure variation ...

For the implementation of time-critical decision support algorithms a precise relation between intervention and effect needs to be established. We evaluated for catecholamines and infusions the relation in time between charted dose and effect on hemodynamic variables. The onset of the change of the hemodynamic variables was determined by autoregressive models. The lag of 13 min (0 29) between i...

The pathologically hypertrophied and failing heart is a battlefield in a war that would make even George Lucas proud. On the one side, you have hemodynamic, neurohormonal, morphological, and cellular/molecular dark forces urging the ventricle toward decompensation and ultimate demise. On the other, Jedi signaling cascades try valiantly to stave off the impending disaster. Alas, unlike the movie...