نتایج جستجو برای: hematopoiesis

تعداد نتایج: 8727  

2010
Raman Sood Milton A. English Christiane L. Belele Hao Jin Kevin Bishop Rebecca Haskins Mary Cathleen McKinney Jagman Chahal Brant M. Weinstein Zilong Wen Paul Liu

Runx1 is required for the emergence of hematopoietic stem cells (HSCs) from hemogenic endothelium during embryogenesis. However, its role in the generation and maintenance of HSCs during adult hematopoiesis remains uncertain. Here, we present analysis of a zebrafish mutant line carrying a truncation mutation, W84X, in runx1. The runx1W84X/W84X embryos showed blockage in the initiation of defini...

Journal: :Developmental & Comparative Immunology 2016

Journal: :Critical Reviews™ in Eukaryotic Gene Expression 2010

Journal: :Frontiers in Cell and Developmental Biology 2018

Journal: :Trends in immunology 2013
Tal Shay Joonsoo Kang

Immunological studies of single proteins in a single cell type have been complemented in recent years by larger studies, enabled by emerging high-throughput technologies. This trend has recently been exemplified by the discovery of gene networks controlling regulatory and effector αβ T cell subset development and human hematopoiesis. The Immunological Genome Project (ImmGen) aims to decipher th...

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