purpose: to report the clinical findings and compare the outcomes of different surgical techniques evolved over time in a large series of patients with delayed-onset mustard gas keratitis (mgk). methods: this interventional retrospective case series includes patients with complications of delayed mgk. medical and surgical interventions to address dry eye, limbal ischemia and limbal stem cell de...

allogeneic hematopoietic stem cell transplantation is used in the treatment of patients suffering from hematologic and non-hematologic disorders, but the application is limited by the identification of a suitable donor. umbilical cord blood (ucb) is an alternative source of hematopoietic stem cell (hsc) transplantation. despite all advantages, the limited cell dose is one of the  major obstacle...

Background Stem cell transplantation has become as a novel treatment  for end-stage kidney, lung, heart , liver diseases and several hematologic disorders. Improved survival of transplant recipients has raised awareness of post-transplant complications. One of these complications is transplant-related osteoporosis. Methods  In this manuscript we review prevention methods for transplant-relat...

abstract spinal cord injury (sci) is a devastating condition producing great personal and societal costs and for which there is no effective treatment. stem cell transplantation is a promising therapeutic strategy, though much preclinical and clinical research work remains. here, we briefly describe sci epidemiology, pathophysiology, and transplantation trial in human developments, including te...

Supportive treatment plays an important role in oncology nowadays. The main aims of oncologic supportive are management cancer symptoms and adverse events treatment.
 In terms dermatologic the most types reaction oral mucositis during radiation therapy, chemotherapy hematopoetic stem cell transplantation, palmoplantar syndrome chemotherapy, skin reaction, acneiform paronychia pyogenic gran...

Background Degenerative retinal diseases, including age related macular degeneration, glaucoma, and hereditary retinal dystrophies are major causes of blindness. The principal defect in these diseases is cell loss which is amenable to both cell based neuroprotective and neuroregenerative therapies. To briefly review the lines of research and potential candidates for cell based therapies among ...

Background: Dendritic cells (DCs) are the most potent stimulators of primary T cell responses and play a key role in immune reactions after stem cell transplantation. Very little is known about the cord blood (CB) dendritic cells and their potential involvement in the low incidence and lower severity of acute graft-versus-host disease after CB transplantation.   Objectives: The aim of this stud...