Sulfation of metabolites is the second highest phase II modification in humans, which plays a critical role xenobiotics clearance process and gut microbiota-host co-metabolism. Besides main function to remove from body, sulfated have also been linked inflammation, bacterial pathogenesis metabolic disorders. A better understanding how these impact human body has turned into an important research...

rhogocytes single cell type: differently responsive metal pools in (Gastropoda) is regulated by one Helix pomatia Copper in You might find this additional info useful... levels of biological organization, ranging from molecules to humans, including clinical investigations. It is published investigations that illuminate normal or abnormal regulation and integration of physiological mechanisms at...

Progress in treatment for cancer has enabled extension of the disease-free interval, and of the quality of life for patients, but there has been very little improvement in overall survival rates. The main reason for this has been the ineffectiveness of current therapies to kill all the cancer cells once they have spread to distant sites to form metastatic deposits. One marker which has proved t...

In gas chromatographic-mass spectroscopic analysis of buprenorphine metabolites, the urine specimen must be first hydrolyzed to release buprenorphine and norbuprenorphine from their glucuronide conjugates. For evaluation of existing hydrolysis methods and to find out the optimal hydrolysis conditions, buprenorphine-3-beta-D-glucuronide (B3G) and norbuprenorphine-3-beta-D-glucuronide (NB3G) were...

Previously reported work on the cardiac physiology of Helix pomatia has been concerned with partly dissected animals or isolated hearts. The present work has been concerned with observing the living animal carrying out normal movements under the minimal amount of experimental interference. The way in which the animal emerges from its shell has also been investigated. During the breathing cycle ...

Ultrastructural analysis of HSB-2 T-lymphoid cells and human cord blood mononuclear cells infected with human herpesvirus 6 revealed the presence, in the cell cytoplasm, of annulate lamellae (AL), which were absent in uninfected cells. Time course analysis of the appearance of AL following viral infection showed that no AL were visible within the first 72 h postinfection and that their formatio...