The myocardial injury that occurs following a period of ischaemia and reperfusion is well recognised and the underlying mechanisms have been extensively investigated in healthy myocardial tissues; however, the influence of the risk factors associated with cardiovascular diseases on ischaemia/reperfusion injury remains unclear. In this article, the present knowledge on how clinical pathologies s...

Background Firearm – related injuries of the thorax and heart are a major problem worldwide. Mortality rate in non-cardiac thoracic injuries is very low compared with that of cardiac injury. Because of the complexity of the injury a gunshot wound to the heart has the highest mortality rate. The rate of thoracic aorta injuries is burdened with a high mortality (80-90%) and management of this inj...

Sudden brain injury in adults can cause pulmonary cedema which may be due to heart failure. In the newborn, heart failure can occur with cerebral damage and lead to diagnostic difficulties, as the cardiac signs are identical with those of congenital heart disease. It is important to be aware that an anatomically normal heart can fail from this cause in the neonatal period, so that correct treat...

objective: several studies have shown that chichorium intybus l. (c. intybus) which possesses flavonoid compounds has an effective role in treatment of cardiovascular diseases. contractile dysfunction mostly occurs after acute myocardial infarction, cardiac bypass surgery, heart transplantation and coronary angioplasty. the aim of the present study was to investigate the effect of aqueous extra...

BACKGROUND While the adult zebrafish (Danio rerio) heart demonstrates a remarkable capacity for self-renewal following apical resection little is known about the response to injury in the embryonic heart. METHODS Injury to the beating zebrafish embryo heart was induced by laser using a transgenic zebrafish expressing cardiomyocyte specific green fluorescent protein. Changes in ejection fracti...

Isoprenaline (ISO) at high doses can cause severe stress to myocardium resulting in an infarct-like necrosis rats. However, its effects repeatedly low dose exposure on heart, kidney and aorta are still unclear. Hence, this study was aimed investigate the of repeated administration ISO organs rats by using Langendorff-perfused isolated hearts, ELISA kits, qPCR histopathology techniques. Male Wis...

We report a case of successful treatment patient with multiple stab and cut wounds chest abdomen which resulted in the injuries venous coronary sinus abdominal organs. Surgical wound revision antishock unit, priorities surgical accesses (thoracotomy laparotomy) allowed timely cure injury. A key feature our is trauma. Coronary suturing closed heart surgery technically difficult. It has potential...

Non-penetrating injuries of the chest wall can give rise to a variety of cardiac lesions. The extent of cardiac damage depends on the intensity of the injury and on pre-existent disease of the heart. In the majority of cases there is a direct blow to the anterior chest wall but serious myocardial damage has been produced by blows directed against the posterior chest wall and abdomen. The crushi...