We proposed that selective decontamination of the digestive tract (SDD) initiated after experimental burn injury would decrease myocardial inflammation and dysfunction after a second insult such as septic challenge. Rats were divided into eight experimental groups. Groups included sham burn plus sham sepsis, burn alone, sepsis alone, and burn plus sepsis given either water by oral gavage for 5 ...

BACKGROUND We examine herein the demographic characteristics, implemented treatment methods, infection rates, and morbidities of patients with tandir burns from two burn centers. METHODS In this study, gender, age, socioeconomic status, total body burn ratio, burn area, burn level, microorganisms isolated in burn wounds, implemented treatments, length of hospital stay, debridement and graftin...

Burn injuries remain a global problem even though they are largely preventable. Adequate knowledge is essential to good burn safety practices. This aids prevention and minimizes severity when burn injuries occur. The purpose of this study was to determine the level of burn safety knowledge among literate adult Nigerians in Ile-Ife and Ilesa, South-western Nigeria. We elicited a paucity of burn ...

BACKGROUND Procedural burn pain is the most intense acute pain and most likely type of burn injury pain to be undertreated due to the physician's fear of the adverse effect of analgesia and lack of anesthetist present. At our institution, in most of the cases, local burn detersion and debridement were performed at the ward level without any analgesics. This article describes a study designed to...

BACKGROUND Burn pain is recognized as being maximal during therapeutic procedures, and wound debridement can be more painful than the burn injury itself. Uncontrolled acute burn pain increases the stress response and the incidence of chronic pain and associated depression. Although opiates are excellent analgesics, they do not effectively prevent central sensitization to pain. The anticonvulsan...

This study profiled intra-oral somatosensory and vasomotor responses to three different transient receptor potential (TRP) channels, subfamily A, member 1 (TRPA1) agonists (menthol, nicotine, and cinnamaldehyde) in smoking and non-smoking young adults. Healthy non-smokers (N = 30) and otherwise healthy smokers (N = 25) participated in a randomized, double-blinded, cross-over study consisting of...

background and purpose: vitamin c is administered orally or intravenously for the treatment of burn wounds. however, effects of the topical application of vitamin c remain unclear. this study aimed to evaluate the effects of topical vitamin c solution on the necrotic tissue volume of second-degree burn wounds. methods: this clinical trial was conducted on 30 patients with second-degree burns ad...

Burn is a global public health problem associated with significant morbidity and mortality, mostly in low- and middle-income countries. Southeast-Asian countries share a big burden of burn injuries, and Nepal is not an exception. We performed a systemic review to examine the epidemiological characteristics of burn injures in Nepal. Relevant epidemiological studies were identified through system...

Cardiomyocyte sodium accumulation after burn injury precedes the development of myocardial contractile dysfunction. The present study examined the effects of burn injury on Na-K-ATPase activity in adult rat hearts after major burn injury and explored the hypothesis that burn-related changes in myocardial Na-K-ATPase activity are PKC dependent. A third-degree burn injury (or sham burn) was given...

Exercise is a key component of burn rehabilitation across all phases of care. Supervised outpatient exercise programs have been shown to improve outcomes following burn injury. However, little is known about the exercise behaviors of burn survivors who do not undertake such programs. This study aimed to investigate self-reported exercise behaviors and barriers to exercise in adult burn survivor...