One of the factors contributing to the increased risk of developing premature atherosclerosis is low plasma concentrations of high-density lipoprotein (HDL) cholesterol (HDLc). Multiple potential mechanisms account for the cardioprotective effects of HDL and its main protein apolipoprotein A-I (apo A-I). The low plasma concentrations of HDL could be the result of increased fractional clearance ...

The relationships among daily physical activity, physical fitness and the risk factors for coronary heart disease (CHD) were studied comparing 477 premenopausal women (36.1 +/- 7.6 yr) and 178 naturally postmenopausal women (56.7 +/- 5.8 yr). The results were as follows. 1) No relationship between physical fitness and daily activity level was found in either groups. 2) In premenopausal women, d...

INTRODUCTION AND OBJECTIVES A large proportion of patients with coronary disease have metabolic syndrome, although the frequency and association of its different components are not well understood. The aim of this study was to determine the prevalence of metabolic syndrome and the combination of its components in a Spanish cohort of patients with acute coronary syndrome. METHODS Clinical hist...

OBJECTIVE To analyze the lipid profile and its correlation with risk factors for cardiovascular diseases (CVD) among medicine students. METHODS We assessed 153 students, regardless of sex, with age between 18 and 31 years old, submitted to lipid profile analysis, including serum levels of total cholesterol (TC), fraction of cholesterol of low (LDLc), high (HDLc) and very low density (VLDLc) l...

The authors examined the association of milk and milk products consumption (MMPC) with serum lipid profiles including total cholesterol (TC), triacylglycerols (TG), HDL cholesterol (HDLC), LDL cholesterol (LDLC), and TC/HDLC ratio in a community-based sample. The study population comprised 461 men and 834 women aged 40-79 years who, in 2001, participated in an annual healthy examination and a l...

INTRODUCTION Pentraxin 3 (PTX3), which is mainly produced by endothelial cells, macrophages, and smooth muscle cells in the atherosclerotic region, has a cardioprotective effect. Endurance exercise training has also been known to offer cardioprotection. However, the effect of regular endurance exercise on PTX3 is unknown. This study aimed to investigate whether plasma PTX3 concentrations increa...

BACKGROUND High-density lipoprotein cholesterol (HDLC) is a strong risk factor for atherosclerosis and is assumed to be under considerable genetic control. We aimed to identify gene regions that influence HDLC levels by a genome-wide association analysis in the population-based KORA (Cooperative Health Research in the Region of Augsburg) study. METHODS AND RESULTS In KORA S3/F3 (n=1643), we a...

Objective: To evaluate various lipid, lipoprotein and apolipoprotein ratios among participants with without metabolic syndrome.
 Study Design: Comparative cross-sectional study.
 Place Duration of Study: Naval Hospital, Islamabad Pakistan, from Jan 2019 to Dec 2020.
 Methodology: We selected 164 patients syndrome. Metabolic syndrome was diagnosed as per “NCEP-defined criteria”. I...

Canine HDL1 and canine and swine HDLc were fractionated into several lipoprotein subpopulations by heparin/manganese precipitation. The ability of the various subfractions of HDL1 or HDLc to compete with 125I-labeled low density lipoproteins (LDL) for binding and degradation by human fibroblasts was compared. The HDL1 or HDLc which precipitated at the lowest concentration of heparin (a concentr...