نتایج جستجو برای: hdag

تعداد نتایج: 88  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پزشکی 1392

هپاتیت b یکی از شایع ترین بیماریهای کبد در جهان می‎باشد، که عامل ایجاد کننده آن عفونت با ویروس هپاتیت b (hbv) است. محدودیت‎های موجود در درمان hbv به همراه پیشرفت‎هایی که درزمینه بیولوژی مولکولی hbv اتفاق افتاده، تلاشها را برای کشف شیوه‎های جدید در مهار تکثیر hbv افزایش داده است. ژنوم بسیار فشرده و هم‎پوشان با عملکردهای مختلف باعث شده تا hbv به عنوان یک هدف مناسب برای درمان بر پایه هیبریداسیون ا...

2013
Kazutaka Shimada Yasuto Seto Mai Omura Kohei Kurihara

This paper describes Japanese textual entailment recognition systems for NTCIR-10 RITE2. The tasks that we participated in are the Japanese BC subtask and the ExamBC subtask. Our methods are based on some machine learning techniques with surface level, syntax and semantic features. We use two ontologies, the Japanese WordNet and Nihongo-Goi-Taikei, and Hierarchical Directed Acyclic Graph (HDAG)...

2015
Zhimin Guo Thomas King Tatsuo Kanda

Chronic hepatitis delta virus infection (CHD) is a condition arising from super-infection of hepatitis B virus (HBV)-infected patients, resulting in a more rapid advance in liver pathology and hepatocellular carcinoma than is observed for HBV mono-infection. Although hepatitis delta virus (HDV) is structurally simple, its life cycle involves the complex participation of host enzymes, HBV-derive...

Farida Behzadian, Farzaneh Sabahi, Leila Shahinsaz Mohsen Karimi Seyed Moayed Alavian Vahid Zand

Hepatitis Delta virus (HDV) is a degenerate RNA virus or virusoid and a satellite of Hepatitis B virus (HBV). Three distinct genotypes are described for HDV; genotype I is distributed worldwide but other genotypes appear to be more restricted geographically. In the present study, an RT-nested PCR method was set up to detect delta infection from serum samples. Moreover, the target amplified sequ...

Journal: :iranian journal of biotechnology 2006
leila shahinsaz farzaneh sabahi mohsen karimi farida behzadian seyed moayed alavian

hepatitis delta virus (hdv) is a degenerate rna virus or virusoid and a satellite of hepatitis b virus (hbv). three distinct genotypes are described for hdv; genotype i is distributed worldwide but other genotypes appear to be more restricted geographically. in the present study, an rt-nested pcr method was set up to detect delta infection from serum samples. moreover, the target amplified sequ...

Journal: :Journal of biotechnology 2005
Yi-Heng Chen Jaw-Chin Wu Kuei-Chun Wang Ying-Wei Chiang Chia-Wei Lai Yao-Chi Chung Yu-Chen Hu

We have recently demonstrated the assembly of hepatitis delta virus-like particles (HDV VLP) by co-transducing hepatoma cells using two recombinant baculoviruses, one encoding hepatitis B surface antigen (HBsAg), and one encoding large delta antigen (L-HDAg). In this study, we further demonstrated the assembly and secretion of VLP in other mammalian cells. The assembly efficiency varied dependi...

2017
Florian A. Lempp Stephan Urban

The human Hepatitis Delta Virus (HDV) is unique among all viral pathogens. Encoding only one protein (Hepatitis Delta Antigen; HDAg) within its viroid-like self-complementary RNA, HDV constitutes the smallest known virus in the animal kingdom. To disseminate in its host, HDV depends on a helper virus, the human Hepatitis B virus (HBV), which provides the envelope proteins required for HDV assem...

Journal: :Nucleic acids research 2003
Chun-Chung Wang Tsung-Cheng Chang Ching-Wen Lin Hsiu-Ling Tsui Page B C Chu Bo-Shun Chen Zhi-Shun Huang Huey-Nan Wu

The N terminal region of hepatitis delta antigen (HDAg), referred to here as NdAg, has a nucleic acid chaperone activity that modulates the ribozyme activity of hepatitis delta virus (HDV) RNA and stimulates hammerhead ribozyme catalysis. We characterized the nucleic acid binding properties of NdAg, identified the structural and sequence domains important for nucleic acid binding, and studied t...

2017
Jing-Hua Zhao Ya-Li Zhang Tian-Ying Zhang Lun-Zhi Yuan Tong Cheng Pei-Jer Chen Quan Yuan Ning-Shao Xia

Hepatitis D virus (HDV) is a defective RNA virus that requires the presence of hepatitis B virus (HBV) for its life cycle. The in vitro HDV infection system is widely used as a surrogate model to study cellular infection with both viruses owing to its practical feasibility. However, previous methods for running this system were less efficient for high-throughput screening and large-scale studie...

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