Hepatitis C virus (HCV) affects 130-210 million people worldwide and is one of the major risk factors for hepatocellular carcinoma. Globally, at least one third of hepatocellular carcinoma cases are attributed to HCV infection, and 350000 people died from HCV related diseases per year. There is a great geographical variation of HCV infection globally, with risk factors for the HCV infection dif...

background: to evaluate the prevalence of hepatitis c by antibody testing, hcv-rna detection by pcr and relative risk fac­tors of hcv infection among hd patients and staff members in markazi province/iran. the other purpose was to deter­mine genotypes of hcv in this population. methods: the study group consisted of 204 hd patients and 47 staff members from all 9 dialysis centers in markazi prov...

We screened for evidence of HCV infection in healthy heterologous monogamous spouses of chronic HCV patients and studied the relation with various risk factors. A cross-sectional study of fifty healthy monogamous heterosexual spouses of HCV-positive index cases was carried out. All participants were HBV and HIV negative. The association with various risk factors was studied. Five spouses (10%) ...

editor considering the increasing prevalence of hcv in diabetes type 2 and chronic nature of hcv infection and its progression to cirrhosis and hepato_cellular tumors, we aimed to determine the frequency of hcv infection in diabetes type 2 in order to diagnose and treat these patients as soon as possible. essential information gathered by a check list from type two diabetic patients admitted at...

MicroRNAs (miRNAs) can exert a profound effect on Hepatitis C virus (HCV) replication. The interaction of HCV with the highly liver-enriched miRNA, miR-122 represents one such unique example of viruses having evolved mechanism(s) to usurp the host miRNA machinery to support viral life cycle. Furthermore, HCV infection can also trigger changes in the cellular miRNA profile, which may ultimately ...

This study aimed to characterize sexual and drug-use behaviors in injecting drug users (IDUs) in relation to single hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infection and HCV/HIV co-infection. The sample consisted of 272 IDUs enrolled in the AjUDE-Brasil I Project, a cross-sectional multi-center study conducted in five Brazilian cities in 1998. Data were collected with a s...

background hepatitis c virus (hcv) infection is the most significant source of chronic liver diseases in the globe. about 170 million individuals are infected by hcv worldwide. the reported prevalence of hcv in different areas of khyber pakhtunkhwa (kp) ranges from 4.1 to 36%. objectives the current study aimed to analyze the true prevalence of hcv infection in khyber pakhtunkhwa, pakistan. mat...

conclusions the high prevalence of hcv infection among this group implies a high rate of transmission and exposure to the risk of serious diseases. it is important that the high prevalence of hcv infection be taken into consideration to control further transmission of this infection. background hepatitis c is an infectious disease caused by blood-borne pathogen, hepatitis c virus (hcv). objecti...

results a total of 6095 participants (36.4% male and 65.6% female) with the mean age of 92 (7-95) and mean ± sd of 34.6 ± 17.3 years were included in this study. fifteen persons (0.24%) were detected as hcv-positive and the highest prevalence was seen in age ≤ 12 years old (1%). a significant association was only detected between blood transfusion and hcv infection; therefore, those persons wit...

Hepatitis B virus/hepatitis C virus (HBV/HCV) dual infection is common among high-risk individuals. To characterize the virological and immunological features of patients with HBV/HCV dual infection, we enrolled 1,049 individuals who have been identified as injection drug users. Patients were divided into single and dual infection groups according to the serological markers. We found the averag...