نتایج جستجو برای: hbv genotypes

تعداد نتایج: 69069  

Journal: :Japanese journal of infectious diseases 2006
Shu-Yun Zhang Hong-Xi Gu Di Li Shu-Fen Yang Zhao-Hua Zhong Xing-Ku Li Xi Jin

Associations were studied between the polymorphism of northern Han Chinese leukocyte antigen (HLA) alleles and the outcomes of hepatitis B virus (HBV) infection and HBV genotypes. HLA-A, B, and DRB1 alleles in peripheral blood mononuclear cells (PBMCs) were detected by polymerase chain reaction (PCR) with sequence-specific primers. The PBMCs were collected from 61 persons who tested positive fo...

2014
Ileana Constantinescu Andrei-Antoniu Dinu Voicu Boscaiu Marius Niculescu

BACKGROUND Accurate and personalized molecular virological diagnosis of hepatitis B virus (HBV) infection is crucial for individualized selection of patients for antiviral therapy in Romania. OBJECTIVES We aimed to investigate HBV mutations in Romanian patients with chronic HBV infection, also to match HBV genotypes with HBV mutations identified and clinical outcomes. PATIENTS AND METHODS T...

2011
Bin Zhou Lei Xiao Zhanhui Wang Ellen T. Chang Jinjun Chen Jinlin Hou

Two forms of hepatitis B virus (HBV) C/D recombinant have been identified in western China, but little is known about their geographical and ethnic distributions, and particularly the clinical significance and specific mutations in the pre-core region. To address these questions, a total of 624 chronic HBV carriers from four ethnic populations representing five provinces in western China were e...

Journal: :hepatitis monthly 0
ileana constantinescu immunology of transplantation discipline, faculty of medicine, carol davila university of medicine and pharmacy, bucharest, romania; center for immunogenetics and virology, fundeni clinical institute, bucharest, romania; centre for immunogenetics and virology, fundeni clinical institute, bucharest, romania. tel: +40-744341984, fax: +40-213180448 andrei-antoniu dinu center for immunogenetics and virology, fundeni clinical institute, bucharest, romania voicu boscaiu “gheorghe mihoc-caius iacob” institute of statistics and applied mathematics, bucharest, romania marius niculescu colentina clinical hospital, bucharest, romania

conclusions genotype d was the main genotype detected in romanian patients with chronic hbv infection. genotype d presented both bcp and pc mutations more frequently. results we detected two hbv genotypes; a (8.1%) and d (60.5%), and a mixture of genotypes a and d (31.4%) (p < 0.001). basal core promoter (bcp) a1762t/g1764a and precore (pc) g1896a mutations were detected in these romanian patie...

Journal: :hepatitis monthly 0
farah bokharaei salim department of virology, iran university of medical sciences, tehran, ir iran; department of virology, iran university of medical sciences, tehran, ir iran. tel/fax: +98-2188602205 hossein keyvani department of virology, iran university of medical sciences, tehran, ir iran seyed hamidreza monavari department of virology, iran university of medical sciences, tehran, ir iran maryam esghaei department of virology, iran university of medical sciences, tehran, ir iran shahin fakhim department of civil engineering, faculty of engineering, payame noor university, karaj, ir iran angila ataei pirkooh department of virology, iran university of medical sciences, tehran, ir iran

conclusions the main and frequent hbv genotype among azerbaijani patients with chronic hepatitis b virus infection was genotype d followed by genotype a. results the mean age of patients was 35.9 ± 11.7 years (19-66). of 103 patients, 72 (69.9%) were male. in the present study, the predominant hbv genotype was d (93.2%) followed by genotype a (5.8%) and concurrent infection with a and d genotyp...

2015
Alexander A. Martínez Yamitzel Zaldívar Griselda Arteaga Zoila de Castillo Alma Ortiz Yaxelis Mendoza Omar Castillero Juan A. Castillo Juan Cristina Juan M. Pascale Isabelle A Chemin

The Hepatitis B Virus (HBV) can cause acute or chronic infection it is also associated with the development of liver cancer, thousands of new infections occur on a yearly basis, and many of these cases are located in certain areas of the Caribbean and Latin America. In these areas, the HBV prevalence is still high which makes this virus a serious public health concern to the entire region. Stud...

2016
Zahra Heidari Bita Moudi Hamidreza Mahmoudzadeh Sagheb Mehrnoosh Moudi

BACKGROUND The host genetic background regulates the natural history of chronic hepatitis B virus (HBV) infection. OBJECTIVES The aim of this study was to investigate the association between TNF-α gene polymorphism in the promoter region and susceptibility to chronic hepatitis B virus infection. METHODS Four polymorphisms of TNF-α gene including -238 A/G, -308 A/G, -857 C/T, and -863 A/C we...

Journal: :Journal of the National Cancer Institute 2005
Ming-Whei Yu Shiou-Hwei Yeh Pei-Jer Chen Yun-Fan Liaw Chih-Lin Lin Chun-Jen Liu Wei-Liang Shih Jia-Horng Kao Ding-Shinn Chen Chien-Jen Chen

BACKGROUND Although chronic infection with hepatitis B virus (HBV) has been established as a cause of hepatocellular carcinoma (HCC), the roles of viral load and HBV genotype remain unclear. METHODS From 1988 through 1992, baseline blood samples were collected from 4841 Taiwanese men who were HBV carriers but had not been diagnosed with HCC. We used real-time polymerase chain reaction assays ...

Journal: :Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2004
J Weiss H Wu B Farrenkopf T Schultz G Song S Shah J Siegel

BACKGROUND Diagnostic assays for the accurate quantitation of hepatitis B virus (HBV) DNA levels from patients undergoing antiviral therapy are useful for monitoring and tailoring therapy. Such assays should give accurate results with all HBV genotypes, including a seventh genotype of hepatitis B virus, genotype G, that has recently been identified in specimens from HBV-positive patients in the...

2010
Mojtaba Oraki Kohshour Hamid Galehdari Ali Mohammad Foroughmand Behnaz Andashti Mohammad Ali Jalalifar Ali Bidmeshkipour

I most Asian countries, with a general carrier rate of 5%–35%, hepatitis B virus (HBV) infection is hyperendemic (1). HBV is a member of Hepadnaviridae, a family of enveloped hepatotropic DNA viruses. It has a circular, partially doublestranded DNA of 3200 nt (2). This virus can cause severe liver disease with eventual progression to cirrhosis and primary hepatocellular carcinoma (HCC) (3). HBV...

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