The demand for an efficient means to manage XML content is increasing proportionately with our increased dependence on XML-based applications, messaging and distributed computing. This white paper examines current market forces, available technology and the emerging XML landscape to gauge the value and, by extension, the demand for an XML-centric database that can sit alongside the many flavors...

T here is now little doubt that the prime cause of the motorneuron disease amyotrophic lateral sclerosis (ALS) is related to misfolding and aggregation of the metalloenzyme Cu/Zn superoxide dismutase (SOD1). Yet, SOD1 has turned out remarkably resistant to aggregation under physiological conditions in vitro. Pathologic mutant proteins that are destabilized to the extent that they fail to fold c...