Among children with recessive metaphyseal dysplasia involving the knees and extremities, two types can be distinguished. In true cartilage-hair hypoplasia, as described by McKusick, many patients show clinical hair involvement and variable immunodeficiency. We present a series of six patients with the same radiological changes, but without apparent hypotrichosis. We suggest that they should be ...

*Jerry Bergman, Ph.D., Northwest State College 22-600 State Rt 34, Archbold, OH 43543 Received April 4, 2003; Revised October 13, 2003 Mammal body hair is a complex structure that involves several basic parts, including a shaft, a root, and a follicle. The most common theory currently in vogue is that hair evolved from reptile scales. Although both scales and hair preserve well in the fossil re...

We report a case of Noonan syndrome with loose anagen hair (NS/LAH), a rare variant of Noonan syndrome, with associated trichorrhexis nodosa and trichoptilosis. The SHOC2 mutation may be responsible for these additional hair shaft defects, revealing the importance of microscopic examination of hairs in these patients.

The presence of melanin in spleens of black C57BL/6 mice has been known for long. Although its origin and biological functions are still obscure, the relation of splenic melanin to the hair follicle and skin pigmentation was suggested. Here, we demonstrated using for the first time electron paramagnetic resonance spectroscopy that black-spotted C57BL/6 spleens contain eumelanin. Its presence he...

© 2017 Indian Dermatology Online Journal | Published by Wolters Kluwer Medknow Trichorrhexis nodosa (TN) is a well‐known entity which affects hair shafts. Clinically, it presents as minute nodular concretions along the hair shaft. This is caused by the loss of cuticle and cortical fibers. On light microscopy, tiny nodules appear as “thrust paint brushes” as if two brushes are thrust into each o...

Short anagen syndrome is an uncommon, probably underreported, condition whose clinical characteristics are poorly recognized and whose incidence is poorly documented in the medical literature. We describe the clinicopathologic features of a child with short anagen syndrome and propose methods for diagnosing this entity by clinical examination, trichogram, light microscopic examination of the ha...

Hair is a significant indicator of health and can have a major impact on an individual’s cosmetic appearance. Research within the cosmetics industry has revealed that when nanomaterials are engineered into hair care, they can enhance the benefits of active ingredients in order to improve hair cosmesis. Within the cosmetics arena, the unique size and intrinsic properties of nanoparticles can be ...

The enzymatic hydrolysis of the particular quality of raw material yield natural free amino acids and low molecular weight peptides in an ideal synergetic mixture. Tests made also directly on hair have shown the excellent properties of KELYAMIN for hair care formulations. The free amino acids are capable of penetrating the hair shaft whereas the peptides with their film-forming properties compl...