VANWYK, J.A. 1999. A comparison of the infectivity of cryopreserved versus unfrozen infective larvae of Haemonchus contortus, Trichostrongylus colubriformis and Trichostrongylus axei: Results of the Onderstepoort Veterinary Institute from 1977 to the present. Onderstepoort Journal of Veterinary Research , 66:285289 The infectivity for sheep of cryopreserved infective larvae (L3) of various stra...

Helminthiasis or infection with gastrointestinal nematodes such as Haemonchus contortus is a common problem in grazing animals which can lead to poor animal performance and economic loss to the livestock industry (Waller & Thamsborg, 2004). In Malaysia, the main methods of controlling gastrointestinal nematodes is using chemical anti-parasitic drug or anthelmintic and also by maintaining good p...

Apart from acting as a source of infection for the lamb, the ewe's parasite status before and after lambing can influence its own productivity and that of the lamb. For example parasitized ewes could give birth to lighter lambs and Gordon (1958) found that infection with Haemonchus contortus reduced milk production. The effects of parasites could be direct or could act indirectly through an eff...

Seven cathepsin B-like cysteine proteases (CBLs) were identified from the immunoprotective excretory-secretory products of Haemonchus contortus. Two-dimensional (2-D) zymography and biotinylated inhibitors were employed to localize active CBLs in 2-D protein gels. Mass spectrometry provided the identification of AC-4, HMCP1, HMCP2, and GCP7 as well as three novel CBLs encoded by clustered expre...

Cholinesterase and acid phosphatase (AP), but not alkaline phosphatase activities, were detected in cytosolic and membrane-bound fractions of ivermectin resistant and susceptible Haemonchus contortus infective-stage larvae. Some differences in acetylcholinesterase activity of cytosolic fractions and in the AP activity of these fractions as well as in the response to AP inhibitors by membrane-bo...

2,4-Disubstituted quinolines with additional substituents in positions 5-8 have been found to have anthelmintic properties. A number of 2,4-dimethoxy-6- or 8-arylquinolines have potent activity against the sheep nematode Haemonchus contortus, with LD99 values of the same order of magnitude as levamisole. These arylquinolines maintain their activity against levamisole-, ivermectin- and thiabenda...

Authors’ addresses: 1 Deviot Institute, Deviot, Tasmania 7275, Australia. 2 School of Human Life Sciences, University of Tasmania, Locked Bag 1320, Launceston, Tasmania 7250, Australia. 3 University Kuala Lumpur, Royal College of Medicine Perak, 3 Greentown Road, 30450 Ipoh, Perak, Malaysia. 4 Institute of Food, Nutrition and Human Health, Massey University, Private Bag 11222, Palmerston North,...

A longitudinal study was conducted on the differential faecal egg counts, haematocrits and body condition scores of sheep belonging to resource-poor farmers at Rust de Winter, Gauteng province, and Kraaipan, North West Province, South Africa. The animals were scored for level of anaemia using the FAMACHA method, an assay for the clinical evaluation of anaemia caused by Haemonchus spp. Periods o...

Resistance to benzimidazoles (BZs) in trichostrongyloid nematodes is a worldwide problem for livestock production, particularly regarding small ruminants. Sensitive and reliable methods are required to assess anthelmintic resistance status. Currently available methods for BZ resistance detection can be divided into three main groups, in vivo (e.g. faecal egg count reduction test), in vitro (e.g...