This study presents micromechanical finite-element FE and discrete-element DE models for the prediction of viscoelastic creep stiffness of asphalt mixture. Asphalt mixture is composed of graded aggregates bound with mastic asphalt mixed with fines and fine aggregates and air voids. The two-dimensional 2D microstructure of asphalt mixture was obtained by optically scanning the smoothly sawn surf...

Cell-cell reconnection after isolation or during healing process after injury is a cell membrane function. It is assumed that each tissue has its own architecture and accordingly, cells in different tissues could have different adaptability to resume their tissue-specific architectures. How membranes adapt themselves to make cell-cell reconnections has not been elucidated. This study investigat...

In this paper we apply vector field topology methods to a mathematical model for the fluid dynamics of reaggregation processes in tissue engineering. The experimental background are dispersed embryonic retinal cells, which reaggregate in a rotation culture on a gyratory shaker, according to defined rotation and culture conditions. Under optimal conditions, finally complex 3D spheres result. In ...

• Simulating the micromechanical behavior of asphalt mixes during compaction using DEM. Representing interactions a viscoelastic contact model. The influence temperature on process and compactability. Analyzing internal structure air-void distribution compaction. paper aims to simulate mixtures Discrete Element Method (DEM). between components Porous Asphalt (PA) mixture were represented an Ela...

With the development of the activities in deep sea, the application of the autonomous underwater vehicle (AUV) is very widespread and there is a prominent prospect. The development of an AUV includes many areas, such as vehicle (carrier/platform) design, architecture, motion control, intelligent planning and decision making, etc (Blidberg 1991; Xu et al., 2006). The researchers dedicate themsel...

Embryonic chick muscle cells were used to investigate the effect of removing cell-surface sialic acids on cell aggregation in vitro. Single cell suspensions were prepared by dissociating skeletal muscle tissue of 9-day-old chick embryos with either crystalline or crude trypsin. Cell aggregation was quantitatively estimated by turbidimetric and gyratory shaker methods. Cells dissociated with cru...

Cells dissociated with 0-25 % crude trypsin from the muscle tissue of 9-day-old chick embryos were employed to investigate the effect of puromycin on cellular metabolism. Parallel studies were also made, using the gyratory shaker, to confirm the effectiveness of puromycin in inhibiting cell aggregation and protein synthesis. Puromycin when introduced at a concentration of io/<g/ml into a suspen...

Flexible pavements comprise about 93 percent of paved roads in the United States. Although flexible pavements are widely used for reasons such as cost, constructability and consistent performance, they are often subject to severe rutting. Rutting is the accumulation of longitudinal depressions under the wheelpaths caused by the repeated traffic loads. Rut is a major concern for the integrity of...

Free hydroxyproline inhibits the growth of animals1' I and plants.3-7 The mechanism of this inhibition is not known. Among the theoretically possible effects of hydroxyproline are: (1) reduction of protein synthesis by lowering proline incorporation, (2) interference with proline hydroxylation, and (3) direct incorporation of hydroxyproline resulting in nonfunctional proteins. Hydroxyproline re...

The mechanisms involved in the mutual attachments of cells and in selectivity of cell contacts are of major interest in studies on growth, developmental interactions, and differentiation in multicellular systems (recent reviews'). With the advent of procedures for dissociating tissues into cells and for controlled reaggregation of single cells into tissues, various aspects of these problems bec...