Background and Objectives: Guillain-Barre ́ Syndrome (GBS) is an acute-onset, monophasic, immune-mediated polyneuropathy that often follows an antecedent infection. Special nutritional support has an important role in these patients. Methods: A 6 years old girl with GBS was admitted to NICU of Dr. Sheikh Children Hospital (Tehran, Iran). Chief compliance for hospitalization was inability to walk...

Although peripheral neuropathies are commonly observed in patients with non-Hodgkin's malignant lymphomas (NHML), Guillain-Barre syndrome (GBS) belongs to the occasional complications of lymphoproliferative disorders. It appears in less than 0.3 per cent of NHML. It is worthy of note that in the reported case there occurred three independent risk factors of peripheral neuropathy: Burkitt's lymp...

Bickerstaff Brainstem Encephalitis (BBE) is a post-infectious immune disorder. It is rare, yet the most severe variant of Guillain-Barre Syndrome (GBS) in terms of initial presentation. Moreover, the coexistence of BBE and Acute Lymphoblastic Leukaemia (ALL) is distinctly uncommon. We report a case of a patient with a background history of Precursor B cell Acute Lymphoblastic Leukaemia (pre B A...

Guillain-Barn! syndrome is a subacute inflammatory demyelinating polyradicular neuropathy of the peripheral nerves. It is characterized by varying degrees of weakness, sensory abnormalities, and autonomic dysfunction. The cause of Guillain-Barre syndrome is not completely understood, but it is believed to be a postinfectious autoimmune disorder, because approximately two thirds of all cases are...

To investigate whether antecedent cytomegalovirus (CMV) infections in patients with Guillain-Barre syndrome are associated with the presence of specific antiganglioside antibodies, acute phase serum samples from 130 patients with Guillain-Barre syndrome and 200 controls were tested. Anti-GM2 IgM antibodies were found more often in patients with Guillain-Barre syndrome with CMV infection (22%) t...

A case of Acute Transverse Myelitis (ATM) is presented. ATM is a rare disease in childhood. The diagnosis stems from the clinical presentation, cerebrospinal fluid findings, appearance of the spinal cord on imaging and ruling out differential diagnoses like Guillain-Barre syndrome (GBS) and Poliomyelitis. The proposed treatment is intravenous (IV) methyl prednisolone with variable chances of re...

Objective Guillain-Barre syndrome (GBS) is the most common cause of acute weakness in children. It has multiple variant forms with different presentations. A rare initial sign is ptosis. In this study, we present a 10-year-old girl with bilateral ptosis without opthalmoplegia followed by a weakness in extremities with a favourable response to intravenous immunoglobulin. Due to the patient's ini...

BACKGROUND Guillain-Barre Syndrome (GBS) is an acute monophasic demyelinating neuropathy characterized by progressive motor weakness of limbs with areflexia. AIM To study the clinical pattern and outcome of children with Guillain-Barre syndrome. MATERIALS AND METHODS It was a cross-sectional study conducted in a pediatric unit of tertiary care hospital over a period of 18 months. We assesse...


 Background Guillain-Barre syndrome (GBS) has a highly diverse clinical course and prognosis. Predicting functional outcomes is needed in order to give appropriate treatment counseling. Erasmus Guillaine-Barre Syndrome Outcome Score (EGOS) simple scoring based on age onset, pre existing diarhea GDS score obtained from medical record physical findings that can be used by clinician predict ...