Infections of the neonate due to the group B Streptococcus have been recognized since the 1930s, but it was during the 1970s that their incidence grew alarmingly throughout the world. A research effort stimulated by this problem has yielded significant new information about many facets of the pathogenesis of these infections. Immunologic investigations have pinpointed a lack of transplacentally...

In 2002, revised guidelines for preventing perinatal group B streptococcal disease were published. In 2002, all Minnesota providers surveyed reported using a prevention policy. Most screen vaginal and rectal specimens at 34-37 weeks of gestation. The use of screening-based methods has increased dramatically since 1998.

Group B streptococcus (GBS) causes multiple diseases, most of which affect neonates and the elderly. In newborns, infection can result in stillbirth, neonatal pneumonia, sepsis, meningitis, mental retardation and hearing or vision loss in children who survive infection. Group B streptococci are common inhabitants of the gastrointestinal and genitourinary tract.5 Less commonly, they colonize the...

A study of 866 vaginal swabs from non-pregnant women showed that 167 (19.3%) contained Group B beta-haemolytic streptococci, with a predominance of Types 3 (31.4%) and Ib (25.2%). The incidence of severe neonatal infections due to Group B streptococci during a 3 1/2 year period at The Prince of Wales Hospital was examined, and a study was made of the distribution of serotypes and associated cli...

The incidence of disease caused by the Group B streptococci (GBS) has risen significantly in the past two to three decades and the GBS are now a leading cause of meningitis in the neonate. The GBS are sub-classified into five groups (Ia, Ib, Ic, II, and III) with type III being the most common, especially in meningitis. The two syndromes, early (first week) and the late (second to twentieth wee...

We report three cases of group B streptococcal endocarditis of the tricuspid valve. Two patients were intravenous drug abusers. In the literature review, and including our cases, ten patients had group B streptococcal endocarditis of the tricuspid valve. Half of the patients were intravenous drug abusers. Four of the other patients had underlying conditions. All patients were treated with a pen...

Elderly adults account for >40% of persons with invasive group B streptococcal (GBS) disease and for >50% of GBS-associated deaths in the United States. The prevalence of colonization among healthy elderly adults (approximately 25%) is similar to that among women of childbearing age. Delineating contributions of comorbid conditions, altered integrity of anatomical barriers, and abnormalities in...

OBJECTIVE In a large private tertiary care hospital we compared the two different approaches to group B streptococcal screening and intrapartum chemoprophylaxis suggested by The American College of Obstetricians and Gynecologists, the American Academy of Pediatrics, and the Centers for Disease Control and Prevention: risk factor-based protocol and culture-based protocol. STUDY DESIGN A 2-year...

Streptococcal sepsis in neonates is a potentially lethal condition. A wide spectrum of clinical presentations has been often reported in Group B Streptococcal infections in neonates. Bone and joint infections which are caused by Group B Streptococcus are also encountered frequently, but they have not yet been reported in case of Group A Streptococcal infection in neonates. Here, we are reportin...