• Bentonite fining is widely used to increase the protein stability of a wine. Some authors have proposed treatment of the juice itself, rather than the wine, to enhance fermentation performance and flavor, and increase stability. Some authors have reported that this practice yields stable wines not requiring further fining, whereas others have found no increase in stability when treating the j...

IN THAI ........................................................................................ I ABSTRACT IN ENGLISH................................................................................. III ACKNOWLEDGEMENTS ................................................................................ V CONTENTS........................................................................................

The presence of grape and wine polyphenol resveratrol (RES) in the diet is negligible. Therefore, the cardiovascular benefits of this molecule, in a dietary context, remain to be established. We aimed to investigate, through dietary intervention, the effects of a resveratrol-rich grape extract (GE-RES) on the prevention of early aortic lesions in pigs fed an atherogenic diet (AD). These effects...

Grape skin and turmeric extracts having the major components resveratrol and curcumin, respectively, were used for the induction of cryptic and bioactive metabolites in an endophytic fungus Colletotrichum gloeosporioides isolated from Syzygium cumini. The increase in total amount of crude compounds in grape skin and turmeric extract treated cultures was 272.48 and 174.32%, respectively, compare...

Ionizing radiation (IR) causes oxidative stress through overwhelming generation of reactive oxygen species (ROS) in the living cells leading the oxidative damage further to biomolecules. Grapevine (Vitis vinifera L.) posses several bioactive phytochemicals and is the richest source of antioxidants. In this study, we investigated V. vinifera for its phytochemical content, enzymes profile and, RO...

The aim of this study was to investigate the protective role of red grape seed extracts (GSEs) against oxidative damage on DNA, brain and erythrocytes in vitro. In this study, the protective effects of two GSEs (water and ethanol) on free radical mediated DNA-sugar damage, Fe -induced lipid peroxidation in brain and 2+ H O induced hemolysis and lipid peroxidation of erythrocytes were determined...

Proanthocyanidins, extracted from grape seeds, are widely used mainly as nutritional supplements. However, there has not been a systematic report to investigate toxicological studies on proanthocyanidins, especially in oral administration. In our studies, proanthocyanidin-rich extract from grape seeds was subjected to a series of toxicological tests to document its safety for use in various foo...

Fruits, such as grapes, are essential food of the Mediterranean diet. Grape extracts have potent antioxidant and chemopreventive properties in vitro. Numerous studies have examined the effects of plant extract administration on redox status at rest in animals and humans but their results are controversial. However, there are no studies comparing the in vitro and in vivo effects of plant extract...

This study was carried out to evaluate the effect of heating and physical conditions of grape seeds on the antioxidant activity of their extracts. Two forms of grape seeds, whole and powdered forms, were heated at four different temperatures 50, 100, 150 and 200 C. After heating, grape seeds were extracted with 70% ethanol (0.1 g grape seed/10 mL of 70% ethanol), and total phenol contents (TPC)...