We have measured 29 pesticides in plasma samples collected at birth between 1998 and 2001 from 230 mother and newborn pairs enrolled in the Columbia Center for Children's Environmental Health prospective cohort study. Our prior research has shown widespread pesticide use during pregnancy among this urban minority cohort from New York City. We also measured eight pesticides in 48-hr personal air...

On a goose farm with 7600 geese kept in 6 houses, 730 birds in 2 houses died within a single day. After drinking, a certain proportion of geese in the affected houses exhibited trembling, salivation, lachrymation and respiratory distress followed by convulsions, dullness and prostration. The birds died soon after the onset of clinical signs. Postmortem examination revealed the presence of a lar...

Pesticide exposure has repeatedly been associated with cancers. However, molecular mechanisms are largely undetermined. In this study, we examined whether exposure to diazinon, a common organophosphate that has been associated with cancers, could induce DNA methylation alterations. We conducted genome-wide DNA methylation analyses on DNA samples obtained from human hematopoietic K562 cell expos...

Widespread contamination of California water bodies by the organophosphate insecticides diazinon and chlorpyrifos is well documented. While their usage has decreased over the last few years, a concomitant increase in pyrethroid usage (e.g., permethrin) (replacement insecticides) has occurred. Vegetated agricultural drainage ditches (VADD) have been proposed as a potential economical and environ...

The recent (late 2001) federally mandated phaseout of diazinon and chlorpyrifos insecticide use in outdoor urban settings has resulted in a rapid decline in concentrations of these insecticides in urban streams and rivers in the northeastern and midwestern United States. Assessment of temporal insecticide trends at 20 sites showed that significant step decreases in diazinon concentrations occur...

Diazinon is a widely used organophosphorus pesticide in agriculture and environmental health, hence its adverse effects on non target animals, especially on fish is to be determined. The present research is conducted to study the influence of diazinon [0, 0-diethyl 0-(2-isopropyl-6-methylpyrimidin-4yl) phosphorothioate] on acetylcholinestrase (AChE) and lipidperoxidation (LPO) on freshwater com...

The photodegradation of the organophosphorus insecticide diazinon with a high probability to contaminate aquatic environments under simulated solar light irradiation conditions on natural water of a river in North of Iran has been studied. During exposure to solar natural light, diazinon is broken down and produced photoproducts in environment. The degradation of the insecticide was a 32 hour p...

The cereal leafminer, Syringopais temperatella Led. (Lep., Scythrididae) is considered one of the most serious insect pests that infests wheat in field, and causes economic damages to crop Jordan. However, little attention has been paid susceptibility common cultivars no combined use tillage regime insecticides against S. temperatella. Concomitan tly, this study aimed at investigating commonly ...

Constructed wetlands for mitigation of nonpoint agricultural runoff have been assessed for their ability to decrease potential toxicity from associated contaminants. After a simulated runoff event, constructed wetlands positioned in series were used to measure the effects of the organophosphate insecticide diazinon. Water, sediment, and plant samples from five sites were analyzed for diazinon c...

Developing embryos are more vulnerable than adults to acute cholinergic intoxication by anticholinesterases, including organophosphorus pesticides. These agents affect the process of neural development itself, leading to permanent deficits in the architecture of the nervous system. Recent evidence on direct roles of acetylcholinesterase (AChE) on neuronal differentiation provides additional gro...