An off-the-shelf vascular graft biomaterial for vascular bypass surgeries is an unmet clinical need. The vascular biomaterial must support cell growth, be non-thrombogenic, minimize intimal hyperplasia, match the structural properties of native vessels, and allow for regeneration of arterial tissue. Electrospun recombinant human tropoelastin (rTE) as a medial component of a vascular graft scaff...

Application of cellulose microfibers as a reinforcing agent for high-performance polyurethane composites is rarely mentioned because the inherent hydrophilicity combined with adverse aspect ratio fibers cause difficulties in dispersion within and compatibility polymer matrix. Here, we propose feasible approach to graft oligoethers synthesized by ring-opening polymerization heterogeneous reactio...

Background: Abdominal wall injuries are commonly encountered in veterinary medicine and may lead to significant complications if not appropriately treated. Different types of grafts, including autologous, xenogeneic, biologic or non-biologic composite widely used ensure adequate tissue repair prevent recurrence cases hernia. However, identifying the most suitable graft for each case is particul...

Although intrastriatal transplantation of fetal cells for the treatment of Parkinson's disease had shown encouraging results in initial open-label clinical trials, subsequent double-blind studies reported more debatable outcomes. These studies highlighted the need for greater preclinical analysis of the parameters that may influence the success of cell therapy. While much of this has focused on...

PURPOSE To retrospectively review our experience with pediatric renal transplantation and to compare the results with the adult population. PATIENTS AND METHODS Between January 1981 and August 2003, 74 renal transplants were performed in patients < or =18 years at the time of the transplant--the pediatric group versus 1153 patients in the adult group. We analyzed various risk factors for actu...

Heavily irradiated mice have been protected from otherwise lethal bone marrow damage by intravenous injection of rat bone marrow."'S5'14 It has been amply demonstrated that the radio-protection offered by the rat bone marrow is actually due to myelopoietic repopulation of the mouse marrow cavity by rat marrow precursor cells."",'8 13 l Mice given supralethal irradiation plus rat bone marrow hav...

it is difficult to reconstruct an alar defect with cartilage involvement. here in the authors report a case of traumatic alar loss during childhood in which an alar reconstruction was carried out with a composite auricular graft put over the pedicle buccal flap which was rotated and passed through the intraoral side. the lining skin and auricular cartilage for the flap was obtained from the aur...