High-grade gliomas are highly vascularized tumors. Neo-angiogenesis plays a key role in tumor growth and resistance to therapy. A cerebrospinal fl uid (CSF) sample could be a useful way to obtain pro-angiogenic predictive or prognostic markers at diff erent stages of the disease. As a fi rst step we looked for pro-angiogenic activity in the CSF of patients with high-grade gliomas. We performed ...

A scoring system specific for day 3 embryos has not been extensively explored. Most IVF laboratories continue to grade embryos solely on the basis of cell number and percentage fragmentation as was traditionally done for day 2 embryos. Additional morphological features, some unique to day 3 embryos, may be useful in selecting embryos most likely to blastulate and implant. The objective of this ...

We determined whether supplementation of a blend of bioactive peptides and oligosaccharides to support immune function (Nutrition Horizons Grade OneTM; Brookville, OH; US Patent no. 6,962,718) would alter quality, stage, and fertilization rate of embryos recovered after superovulation. Cows were superovulated using follicle stimulating hormone as NIH-FSH-P1 and were stratified by breed before r...

To find some prognostic factors for the outcome of frozen-thawed cycles, we have retrospectively analysed all frozen pre-embryos that were thawed during 1993 and 1994 at two in-vitro fertilization (IVF) units in Sweden. Supernumerary pre-embryos were frozen from 551 oocyte retrievals and these resulted in 660 frozen-thawed cycles which lead to 623 thawed embryo transfers. The outcome of these t...

Objective To analyse factors influencing the outcome of frozen-thawed embryo transfer (FET) Method A retrospective analysis was performed in our center on 129 thawing cycles from March 2001 to April 2003. The related parameters were compared between conceived and non-conceived cycles. Results There were totally 129 clinical pregnancies in these transfers (pregnancy rate: 27.1%). Frozen-thawed e...

BACKGROUND Embryo quality may be accurately assessed as early as the pronuclear zygote phase, as shown in recent studies. However, it is not known whether good quality zygotes are destined to become good quality cleavage stage embryos and blastocysts. METHODS In this retrospective study, 86 intracytoplasmic sperm injection-embryo transfer cycles were studied where each available embryo was sc...

background: it has been demonstrated that performing a mock embryo transfer (et) significantly improves the pregnancy rate in ivf cycles. the mock et could be performed prior to the stimulation cycle or immediately before real et. the problem of the first procedure is the possibility of variation in the uterine position and or cervico�uterine angle. objective: the purpose of this study was to d...

background: natural endometrium in frozen-thawed embryo transfer (fet) may have some benefits upon implantation in patients with repeated implantation failure (rif). it might be due to possible differences between natural and stimulated endometrial growth factors and cytokins secretions. objective: the objective of this study was to compare the pregnancy rate of fet on modified natural cycle ve...

Background: A prerequisite for successful embryo implantation is adequate preparation of receptive endometrium and the establishment and maintenance of a viable embryo. The success of implantation further relies upon a two-way dialogue between the embryo and uterus. However, molecular bases of these preimplantation and implantation processes in humans are not well known. Materials and Methods: ...

This retrospective study examines the influence of recombinant growth hormone (rGH) and melatonin adjuvants on oocyte numbers, embryo utilization live births arising from 3637 autologous IVF±ICSI treatment cycles undertaken 2376 women across ten years (2011-2020) within a pioneer Australian facility. Despite using an FSH-dosing algorithm enabling maximal doses up to 450 IU for with reduced ovar...