The cellular uptake of gold nanoparticles (AuNPs) may (or may not) affect their speciation, but information on the chemical forms in which the particles exist in the cell remains obscure. An analytical method based on the use of capillary electrophoresis hyphenated with inductively coupled plasma mass spectrometry (ICP-MS) has been proposed to shed light on the intracellular processing of AuNPs...

Highly refined shape populations of gold nanoparticles (AuNPs) are important for emerging applications in catalysis, plasmonics, and nanomaterials growth. To date, research efforts have focused on achieving monodisperse shape by synthetic control or postsynthetic processing that relies on centrifugal sedimentation-based sorting schemes where differences in the particle mass and aspect ratios (e...

A highly sensitive dynamic light scattering (DLS) assay for glucose detection without interference from ascorbic acid was demonstrated based on mercaptophenylboronic acid functionalized gold nanoparticles (MPBA-AuNPs). The stable, water-solubility MPBA-AuNPs were synthesized using facile and mild method. In the presence of glucose, specific binding between glucose and boronic acids resulted in ...

Nanotechnology is recently emerging in various fields especially in biomedical applications as many pathogenic organisms are gaining resistant against available antibiotics. In the present study, we have synthesized biocompatible therapeutic gold nanoparticles using Brevibacillus formosus isolated from the Hutti gold mine, India. Gold nanoparticles (AuNPs) synthesised by the reduction of gold c...

Introduction: In this study, we explore in detail cell-specific targeting efficacy of nano-photo-thermal therapy (NPTT) method and the resulting responses that are induced by variable laser intensities and exposure times in cancer cells to induce selective apoptosis. We delineate the synthesis of a high-yielding synthetic F-AuNPs by tailoring the surface of gold nanoparticles ...

Gold clusters with controlled sizes have been prepared by controlled self-assembly of citrate stabilized gold nanoparticles (AuNPs) with temperature-responsive luminescent amphiphilic dendrimers (Den 40) of oligo(p-phenylene vinylene) core branches and oligo(ethylene oxide) terminal chains. The shape and size of the resultant gold clusters depend strongly on the molar ratio of Den 40 to AuNPs. ...

Early diagnosis of typhoid is a worldwide concern since the conventional Widal test or Tube agglutination test is questionable for its limitations in terms of delayed implementation and false negative response for detection of Salmonella typhi (the most common food / water borne causative of typhoid) [1-2]. An improved and specific DNA hybridization electrochemical biosensor using direct electr...

A sensitive electrochemical sensor was fabricated for selective detection of nitric oxide (NO) based on electrochemically reduced graphene (ErGO)-polyaniline (PANI)-gold nanoparticles (AuNPs) nanocomposite. It was coated on a gold (Au) electrode through stepwise electrodeposition to form AuNPs-PANI-ErGO/Au electrode. The AuNPs-PANI-rGO nanocomposite was characterized by Field Emission Scanning ...

Nanocarrier design combined with pulmonary drug delivery holds great promise for the treatment of respiratory tract disorders. In particular, targeting of dendritic cells that are key immune cells to enhance or suppress an immune response in the lung is a promising approach for the treatment of allergic diseases. Fluorescently encoded poly(vinyl alcohol) (PVA)-coated gold nanoparticles, functio...

A signal-off impedimetric immune-biosensor based on gold nanoparticle (AuNP)-mediated electron transfer (ET) across a self-assembled monolayer (SAM) was the developed for highly sensitive detection of Escherichia coli O157:H7 bacteria. The biosensor was fabricated by covalently grafting an anti-Escherichia coli O157:H7 antibody onto SAM-modified gold electrodes. Following bacterial capture, the...