Human gnathostomiasis is characterized by space-occupying inflammatory lesions and/or hemorrhage as a result of the migration of, very often, a single larva of Gnathostoma spinigerum. Intermittent cutaneous migratory swellings occurring over years is the most common manifestation and the rare cerebral invasion may be fatal. There are currently no effective anthelminthics for this infection. Dur...

This was a retrospective study of patients having Gnathostoma antibody testing at the Hospital for Tropical Diseases, Bangkok during 2000-2005 to investigate predictive factors for Gnathostoma seropositivity in patients attending the Gnathostomiasis Clinic. Out of 849 patients tested, 531 (62.5%) were Gnathostoma seropositive. The median absolute eosinophil counts were 464 (0-16,796) and 326.5 ...

The phylogenetic relationships and molecular differentiation of three species of angiostrongylid nematodes (Angiostrongylus cantonensis, Angiostrongylus costaricensis and Angiostrongylus malaysiensis) were studied using the AC primers for a 66-kDa protein gene of A. cantonensis. The AC primers successfully amplified the genomic DNA of these angiostrongylid nematodes. No amplification was detect...

Between August 2000 and August 2001, 12,216 fish of 73 species were purchased from several local markets in Nakhon Nayok Province, Thailand, and examined for the presence of Gnathostoma larvae. Almost all species were fresh-water fish that had grown naturally, rather than raised commercially. Eight species were found to be infected with gnathostome larvae. The overall prevalence was 5.1% (626/1...

4. Dani CMC, Mota FK, Sanchonette VP, Maceira JP, Maia APC. Gnathostomiasis in Brazil: case report. An Bras Dermatol. 2009;84:400–4. http://dx.doi.org/10.1590/ S0365-05962009000400012 5. Katchanov J, Sawanyawisuth K, Chotmongkol V, Nawa Y. Neurognathostomiasis, a neglected parasitosis of the central nervous system. Emerg Infect Dis. 2011;17:1174–80. http://dx.doi.org/10.3201/eid1707.101433 6. I...

Gnathostoma spinigerum is an uncommonly encountered parasite, even in a practice such as ours, which hosts a Traveler's Clinic and provides care for a relatively large Southeast Asian population. Gnathostomiasis is most commonly reported in Asia, particularly Thailand and J apan.1 N onetheless, gnathostomiasis is a potentially serious, even life-threatening, parasitosis that can be seen in any ...