Total glycosylated haemoglobin (HbA1) levels from capillary blood were studied retrospectively during a 1-year period in 148 diabetic children aged between 1.9 and 16.8 years. The clinic range for HbA1 was 6.7 to 22.2% and the results were normally distributed (mean +/- SD 13.2 +/- 2.8%). The normal range in non-diabetics using this method is 4.9 to 8.0%. Results from children who had had diabe...

W e thank Drs. Kilpatrick and Bloomgarden (1) for their interest in our study. While we agree that the higher mean HbA1c in blacks compared with whites is well established, the collective evidence suggests that risk associations are similar. The goal of our recent study (2) was to compare the prognostic value of HbA1c to fasting glucose for risk of major complications in black and white adults....

The link between glucose and HbA1c at steady state has previously been described using steady-state or longitudinal relationships. We evaluated five published methods for prediction of HbA1c after 26/28 weeks using data from four clinical trials. Methods (1) and (2): steady-state regression of HbA1c on fasting plasma glucose and mean plasma glucose, respectively, (3) an indirect response model ...

OBJECTIVES We sought to determine whether literacy mediates the relationship between education and glycemic control among diabetes patients. METHODS We measured educational attainment, literacy using the Short Test of Functional Health Literacy in Adults (s-TOFHLA), and glycemic control (HbA1c) in 395 diabetes patients at a U.S. public hospital. We performed path analysis to compare two compe...

To determine the effectiveness of hemoglobin A1c (HbA1c) ≥ 6.5% in diagnosing diabetes compared to fasting plasma glucose (FPG) ≥ 126 mg/dL and 2-hour plasma glucose (2hPG) ≥ 200 mg/dL in a previously undiagnosed diabetic cohort, we included 5,764 adult subjects without established diabetes for whom HbA1c, FPG, 2hPG, and BMI measurements were collected. Compared to the FPG criterion, the sensit...

Author details Department of Biostatistics, The University of Liverpool, Liverpool L69 3BX, UK. Alder Hey Children’s NHS FT, East Prescott Road, Liverpool L12 2AP, UK. Professor in Paediatric Endocrinology & Honorary Consultant, Division of Population Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. Department of Biochemistry, Alder Hey Children’s NHS FT, East...

background many sufferers of type i diabetes, as they are young, need support in order to be able to continue their care; therefore, to have social support could have a role in improving the metabolic control. accordingly, the present study was done in order to determine the perceived social support and its relationship to the glycosylated hemoglobin in the children and adolescents who suffer f...

INTRODUCTION AND OBJECTIVES In patients with heart failure and type 2 diabetes, low glycosylated hemoglobin has been related with higher risk of mortality but information regarding morbidity is scarce. We sought to evaluate the association between glycosylated hemoglobin and 30-day readmission in patients with type 2 diabetes and acute heart failure. METHODS Glycosylated hemoglobin was measur...