Mycobacterium colombiense is a novel member of the Mycobacterium avium complex, which produces respiratory and disseminated infections in immunosuppressed patients. Currently, the morphological and genetic bases underlying the phenotypic features of M. colombiense strains remain unknown. In the present study, we demonstrated that M. colombiense strains displaying smooth morphology show increase...

In an effort to model the observed energy spectrum of Cygnus X-1 as well as its hard X-ray lag by Comptonization in inhomogeneous clouds of hot electrons with spherical geometry and various radial density profiles we discovered that: 1) Plasma clouds with different density profiles will lead to different Comptonization energy spectra even though they have the same optical depth and temperature....

To interpret LC-MS/MS data in proteomics, most popular protein identification algorithms primarily use predicted fragment m/z values to assign peptide sequences to fragmentation spectra. The intensity information is often undervalued, because it is not as easy to predict and incorporate into algorithms. Nevertheless, the use of intensity to assist peptide identification is an attractive prospec...

We report on intermittent X-ray pulsations with a frequency of 442.36 Hz from the neutron-star X-ray binary SAX J1748.9–2021 in the globular cluster NGC 6440. The pulsations were seen during both 2001 and 2005 outbursts of the source, but only intermittently, appearing and disappearing on timescales of hundreds of seconds. We find a suggestive relation between the occurrence of type-I X-ray bur...

MOTIVATION Owing to recent advancements in high-throughput technologies, protein-protein interaction networks of more and more species become available in public databases. The question of how to identify functionally conserved proteins across species attracts a lot of attention in computational biology. Network alignments provide a systematic way to solve this problem. However, most existing a...

We have monitored a sample of 27 nearby globular clusters in the hard X-ray band (20 − 120 keV) for ∼1400 days using the BATSE instrument on board the Compton Gamma-Ray Observatory. Globular clusters may contain a large number of compact objects (e.g., pulsars or X-ray binaries containing neutron stars) which can produce hard Xray emission. Our search provides a sensitive (∼50 mCrab) monitor fo...

PURPOSE The diagnosis of Mycobacterium avium complex pulmonary disease (MAC-PD) can be challenging. A serodiagnosis enzyme immunoassay (EIA) kit, which detects the serum anti-glycopeptidolipid (GPL) core IgA antibody, has been commercialized recently; however, its clinical usefulness in the diagnosis of MAC-PD is still unclear. This study aimed to evaluate the availability of this kit and ident...

Mycobacteria contain species- and type-specific antigens. Among them, glycopeptidolipids are present in medically relevant organisms belonging to Mycobacterium avium or M. fortuitum complexes. Fast-a tom bombardment mass spectrometry of glycopeptidolipids has proven to be difficult. In this article the cationization method with a metanitrobenzyl alcohol matrix, doped with sodium iodide, is desc...