نتایج جستجو برای: glucuronosyltransferase
تعداد نتایج: 2005 فیلتر نتایج به سال:
The Funding statement is incorrect. The publisher apologizes for the error. The complete, correct Funding statement is: This work has been supported partially by a grant from Fundación de Investigación Médica Mutua Madrileña (ref number AP27072008), a grant from Universidad Europea de Madrid (project number 2013/UEM31) and by the help of Cátedra Florencio Tejerina-UEM in blood sample collection...
New approaches to expedite the development of safe and effective pediatric dosing regimens and first-in-child doses are urgently needed. Model-based approaches require quantitative functions on the maturation of different metabolic pathways. In this study, we directly incorporated a pediatric covariate model for the glucuronidation of morphine into a pediatric population model for zidovudine gl...
Conclusion: However, the blue light treatment is less effective with ageing, due to decrease of the blue lightpenetration through skin. Thus, there is a need for alternative treatments. Here, we propose to design de-novopeptide, using this specific RRM frequency. Such peptide, according to RRM, is proposed to have the samebiological function as UDP glucuronosyltransferase 1-A1 and thus can be u...
After the administration of 3-methylcholanthrene to adult male rats, activities of hepatic UDP-glucuronosyltransferase towards six from a group of 12 substrates were stimulated by 250-350%. Activities towards the remaining six substrates were unaffected. Conversely, after phenobarbital administration, activities formerly stimulated by 3-methylcholanthrene remained unchanged, and the other six a...
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