نتایج جستجو برای: glucuronidase
تعداد نتایج: 3231 فیلتر نتایج به سال:
The beige mouse is an animal model for the human Chediak-Higashi syndrome, a disease characterized by giant lysosomes in most cell types. In mice, treatment with androgenic hormones causes a 20-50-fold elevation in at least one kidney lysosomal enzyme, beta-glucuronidase. Beige mice treated with androgen had significantly higher kidney beta-glucuronidase, beta-galactosidase, and N-acetyl-beta-D...
PURPOSE To analyze the levels of β-glucuronidase during prolonged (14 day) corneal preservation with epithelialized (EPI) and deepithelialized (DEP) corneas and the effect of supplemental hydrocortisone (HCT) on these levels. METHODS Thirty-six freshly excised bovine corneas were preserved in Optisol solution (4°C) for 14 days with the following conditions EPI/no supplemental HCT, DEP no supp...
Recombinant mouse beta-glucuronidase administered intravenously to newborn mice with mucopolysaccharidosis type VII (MPS VII) is rapidly cleared from the circulation and localized in many tissues. Here we determine the tissue distribution of injected enzyme and describe its effects on the histopathology in 6-wk-old MPS VII mice that received either one injection of 28,000 U recombinant beta-glu...
Abbreviations: attE: attacin E gene ELISA: Enzyme Linked Immunosorbent Assay gusA: β-glucuronidase gene GUS: glucuronidase nos: nopaline synthase gene nptII: neomycin phosphotransferase II gene NPTII: neomycin phosphotransferase II protein PCR: polymerase chain reaction PTGS: post-transcriptional gene silencing RNA: ribonucleic acid RT-PCR: reverse transcription PCR T-DNA: transfer DNA TGS: tra...
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