This study was conducted to isolate and characterize Paenibacillus sp. MBT213 possessing β-glucosidase activity from raw milk, and examine the enzymatic capacity on the hydrolysis of a major ginsenoside (Rb1). Strain MBT213 was found to have a high hydrolytic ability on ginsenoside Rb1 by Esculin Iron Agar test. 16S rDNA analysis revealed that MBT213 was Paenibacillu sp. Crude enzyme of MBT213 ...

Depression is a common occurrence in patients with Parkinson's disease (PD). Pramipexole is a dopamine agonist that has been used to treat both motor and non-motor symptoms associated with PD. We conducted a study to elucidate the effect of pramipexole on each of the depressive symptoms as assessed by the Zung Self-Rating Depression Scale (SDS). Twenty patients with PD were treated with pramipe...

To examine the significance of tt-glucosidase in starch metabo]ism in vivo, wheat seedlings and seeds were treated with Bay m 1099 (Miglitol, !VLhydroxyethyl-1-deoxynojirimycin), an ct-g]ucosidase inhibitor. Bay m 1099 did not affect germination, but it inhibited growth of seed]ings at the high dosage (100pglml medium).Treatmentofnorma]lygrownseedlingswithBaym1099(1Oand1OO"glml)decreasedor-gluc...

Spring durum wheat is an important raw material for producing diverse products such as couscous, bulgur, bread, and pasta. The quality of the dough significantly influenced by high-molecular-weight glutenins, allelic status which depends on region breeding program. In this study, a collection 69 cultivars promising lines were analyzed state Glu-A1 Glu-B1 using SDS-PAGE KASP PCR markers. Protein...

BACKGROUND Brucea javanica (B. javanica) seeds, also known as "Melada pahit" in Indo-Malay region are traditionally used to treat diabetes. The objective of this study was to determine antidiabetic, antioxidant and anti-inflammatory effects of B. javanica seeds on nicotinamide (NA)-streptozotocin (STZ) induced type 2 diabetic (T2D) rats and to analyze its chemical composition that correlate wit...

Background: Linear growth is the best clinical parameter for monitoring metabolic control in classical congenital adrenal hyperplasia (CAH). Objective: To analyze growth patterns in children with CAH diagnosed by newborn screening and treated with relatively low doses of hydrocortisone during the first year of life. Patients and Methods: 51 patients (27 females) were diagnosed with classical CA...

In the present work we have evaluated the acute toxicity of two anionic surfactants, alkyl benzene sulphonate (ABS) and sodium dodecyl sulphate (SDS) to eggs of gilthead Sparus aurata. At each surfactant concentration, we determined the exposure time required for 50% mortality of the eggs (LT50), surface tension and volume of oil globule in gilthead eggs. Clear dose-response relationships for m...

objective diabetes mellitus is manifested by hyperglycaemia. different treatments such as diets and drugs are recommended for diabetes control. for various reasons in recent years traditional plant (herbal) therapies as prescribed by indigenous systems of medicine with different mechanisms have commonly been used. the digestive enzymes such as alpha glucosidase are among these herbal remedies. ...

BACKGROUND Osteoporosis has been reported in adult patients with inflammatory bowel disease. AIMS To evaluate bone mineral density (BMD), nutritional status, and determinants of BMD in children with inflammatory bowel disease. PATIENTS Fifty five patients (34 boys and 21 girls, age range 4-18) were studied; 22 had Crohn's disease and 33 ulcerative colitis. METHODS Lumbar spine and total b...

The essential phosphatidylinositol kinase homologue TOR2 of Saccharomyces cerevisiae controls the actin cytoskeleton by activating a GTPase switch consisting of RHO1 (GTPase), ROM2 (GEF) and SAC7 (GAP). We have identified two mutations, rot1-1 and rot2-1, that suppress the loss of TOR2 and are synthetic-lethal. The wild-type ROT1 and ROT2 genes and a multicopy suppressor, BIG1, were isolated by...