OBJECTIVES A prospective, open study of corticosteroid hip injection (CHI) was performed to determine if different radiological patterns of arthritis vary in their response. METHODS Forty five patients (15 with rheumatoid arthritis, 27 with osteoarthritis, and three with anklyosing spondylitis) underwent hip injection with 80 mg methylprednisolone and lignocaine under x ray control. Outcome w...

BACKGROUND Acute interstitial nephritis (AIN) is a recognized cause of reversible acute renal failure characterized by the presence of an interstitial inflammatory cell infiltrate. METHODS In order to evaluate the clinical characteristics and management of this disorder, we performed a retrospective study of all cases of AIN found by reviewing 2598 native renal biopsies received at our instit...

the condition was self-limited. Cultures for streptococci were not performed for the partners, who were not described as having systemic complaints, in this study. Carlino and Calzavara [2] described a case of "chronic urethritis" with recurrent attacks of cellulitis. Chlamydiae were isolated at the onset, and group G streptococci were isolated each time the cellulitis recurred. No cultures wer...

We herein describe the case of a 68-year-old man who developed overt diabetes mellitus following the topical administration of dexamethasone 0.1%-containing ointment over a five-month period to treat oral lichen planus. The topical dexamethasone therapy was discontinued gradually, and the patient was subsequently treated with insulin for one month without clinical signs of overt adrenal insuffi...

A number of studies have demonstrated seasonal regulation of the adrenocortical response to stress, or of corticosteroid binding globulins, but very few studies have examined seasonal regulation of corticosteroid receptor levels. As a result, there have been few attempts to produce an integrated picture of seasonal plasticity of the stress response. We measured baseline and stress-induced corti...

background: hyperglycemia is one of the important featurs of diabetes. in cell culture studies different methods are used to mimic the hyperglycemia condition. in this study we investigate response of human liver cancer cell line (hepg2) to high insulin, high glucose, and high insulin/ high glucose medium exposure. methods: hepg2 cells were settled in dmem+0.1% fbs or dmem free-serum medium wit...